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PhD in cell or molecular biology or a related field, ideally with 2 or more years post-degree experience preferably in drug discovery and in an industry setting. Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening (e.g., transfection); cell-based assays ; PCR.
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Expertise in protein design and bioinformatics, including molecular modeling (homology modeling and molecular dynamics simulations) using in silico tools such as MOE, Maestro, NAMD, Schroedinger or VMD, etc.
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Technical Expertise: Experience in high-complexity molecular testing, particularly next-generation sequencing (NGS) molecular diagnostics, and a working knowledge of histology/imaging, and cytology/cytometry methods.
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Extensive hands-on experience with molecular and cell biology techniques (e.g., PCR, Western blot, ELISAs, luciferase assays, flow cytometry, immunocytochemistry/immunofluorescence) is required.
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Demonstrated experience in diverse molecular and biochemical laboratory techniques applied to cell characterization at molecular or genetic levels (immunofluorescence, flow cytometry, qPCR, RNA sequencing)Well organized, self-motivated, team oriented, ability to multitask with attention to detailExcellent communication and writing skillsProficient in computational analysis and coding pipelines (R Studio, Python, etc.
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Develop and implement novel histological and molecular assays to increase disease biology understanding and determine therapeutic efficacy across multiple gene therapy programs. Experience with cell-based and molecular biology assays such as, but not limited to qPCR/ddPCR/dPCR, Western blotting, Immunocytochemistry and ELISA.
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We are seeking candidates for a postdoctoral fellowship focusing on the applications of PET imaging agents and targeted radiotherapeutics while working closely with a team of experts in molecular cancer imaging, molecular biology, immuno-oncology, interventional oncology, and radioligand therapy.
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Strong knowledge of various drug discovery techniques, such as high-throughput screening, molecular modeling, and structure-activity relationship analysis, and CMC awareness. Strong subject matter expertise in immune-oncology, cell therapy drug discovery and development including CMC considerations, CAR design, engineering and armoring strategies, innate immune cells such as NK and gamma delta for the purposes of leading drug development projects from start to the clinic.
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In this role, you will be responsible for executing testing cell and molecular biology assays, as well as basic laboratory maintenance in support of ElevateBio’s gene and cell therapy programs.
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This position is specifically dedicated to the histological analysis of transplanted tissues, including all aspects of tissue preparation, immunocytochemistry, in situ hybridization, microscopy and quantitative imaging, within Sana’s Stem Cell Sciences lab.
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In addition to basic methods of cell and molecular biology including signal transduction pathways, microRNA and long noncoding RNA, transgenics and gene knock out the Chen Lab has used a number of rodent animal models, in which stem cells, growth factors and advanced matrix scaffolds are applied.
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This role involves developing and implementing customer-centric initiatives for molecular diagnostics and life science tools, in line with the global marketing strategy. Minimum of 3-5 years of experience in a marketing role, preferably in molecular diagnostics or immunodiagnostics, and familiarity with OEM and custom commercial supply products.
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Ph. D. in Cell Biology, Molecular Biology, Genomics, or a related field and post-doctoral fellowship. The ideal candidate will have a background in cellular biology, molecular biology, and bioinformatics, with a strong focus on single-cell techniques.
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Preferred Experience and skills: Familiarity with molecular biology techniques, including PCR, restriction enzyme digestion, DNA purification, SDS-PAGE, western blot and microbial transformation (bacteria, yeast.
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Principal duties and responsibilities will include performing cutting edge, bench-level research in the following areas: molecular/cellular biology, human induced pluripotent stem cell (iPSCs) and neural stem cells, cellular differentiation, lineage phenotyping and basic neurobiology.
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molecular tissue jobs Title: post doctoral Company: Emory University in Brookline, MA
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