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M.S. in organic chemistry or biochemistry/chemical biology with a specialization in synthetic methodology, total synthesis, peptide/protein chemistry, oligonucleotide chemistry, or synthetic/conjugation chemistry.
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QUALIFICATIONS: Ph. D. in Chemistry, Organic Chemistry, Nucleoside Chemistry related discipline with minimum 2 years’ experience, preferably in oligonucleotide field. Optimization and scale up of oligonucleotide (Solid phase synthesis) processing method from Lab scale to manufacturing scale.
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Subject matter expert in organic synthesis and methodology, with general knowledge of the mechanisms of chemical reactivity and awareness of latest scientific literature. Doctoral degree (Ph. D.) focused on synthetic organic chemistry or medicinal chemistry with 3+ years of experience in biotech and/or pharmaceutical industry setting (OR M.Sc. degree focused in synthetic organic chemistry with 8+ years of experience), and a strong track record of scientific innovation and success documented through peer-reviewed publications and patents.
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Design, plan and execute multi-step organic synthesis and purification of high-quality target molecules and solve synthetic chemistry challenges to enable expansion of available chemical space.
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Specific experience with phase-change materials, battery electrode manufacturing, organic synthesis, polymer chemistry, additive manufacturing, or composite engineering is a plus. Synthesize organic–inorganic hybrid and organic materials for use as solid refrigerants.
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Is a subject matter expert in the areas of medicinal chemistry, SBDD (structure-based drug design), parallel synthesis and has insights in related disciplines including computational chemistry, chemical biology, drug metabolism, analytical chemistry, and process development.
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Prior experience in methodology/catalysis, total synthesis, chemical biology, bioconjugate chemistry, peptide synthesis, and/or physical organic chemistry. It is expected that the successful candidates will learn quickly through on-the-job training to become increasingly skilled in the design, synthesis, and optimization of complex drug candidates and intermediates, and data driven drug design.
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The successful candidates will contribute to multidisciplinary discovery teams by applying innovative synthetic chemistry, analytical techniques, and data analysis to the design and synthesis of drug candidates and intermediates.
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This role will be focused on developing machine learning algorithms to design molecular structures, forecast chemical properties, and predict the outcomes of organic synthesis. This role will be focused on developing machine learning algorithms to design molecular structures, forecast chemical properties, and predict the outcomes of organic synthesis.
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The ideal individual has a PhD in Biochemistry , Medicinal Chemistry, or Organic Chemistry and 15+ years of industry experience leading automation and high throughput biology/chemistry for target ID, Novel Hit Discovery, Hit to Lead, and Lead Optimization campaigns across multiple target classes and disease areas as a member of the senior leadership team of a small to mid stage biotech company or the R&D organization of a large pharmaceutical company.
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A PhD in Chemistry with 0–1-year experience or MS degree in chemistry with a minimum of 4 years or a bachelor’s degree with 6 years of experience in organic synthesis including synthetic methodology, catalysis, and / or total synthesis along with a proven track record of solving problems.
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Demonstrated laboratory experience in the development of one or more of the following unit operations: liquid phase organic synthesis, crystallization, reaction engineering, or other aspects relevant to fine chemical or drug substance processing.
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Other transactions spanned the scope of our entire business including molecular biology, protein synthesis, life science instrumentation and biologics and drug manufacturing. We have committed to 7-9% long-term organic revenue growth further enhanced by acquisitions.
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Experienced in operating, maintaining, and calibrating synthesis platforms and scientific equipment in an oligonucleotide chemistry lab. or an M.S. in Organic Chemistry, Biochemistry, or a related field with a minimum of 5 years of laboratory experience.
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Bachelor degree in organic chemistry or biochemistry/chemical biology with undergraduate research experience in synthetic methodology, total synthesis, peptide/protein chemistry, oligonucleotide chemistry, or synthetic/conjugation chemistry.
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organic synthesis jobs in Boston, MA
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