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Data Scientist - SIMCA/Python Research Scientist chemometrics PLS models. The scope of the work will include all PAT modeling support for Raman spectroscopy modeling for Invitro transcription (IVT) and capping reactions using SIMCA (a multivariate data analysis software) and Python.
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Work will consist of instrumentation development and the performance of Raman arthroscopy measurements in a series of ex vivo and in vivo model systems to assess the diagnostic capability of the platform.
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Experience with PAT/Chemometrics, Continuous Manufacturing, and/or QbD is preferred. Degree in chemical engineering, pharmaceutical science, materials science, or related physical science with a PhD and 3+ years, or an MS with 10+ years, or a BS with 15+ years of experience in pharmaceutical development.
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Provide strong expertise in biophysical characterization techniques & instrumentations, such as SEC-MALS, CD, DSC/DSF, FT-IR, AUC, DLS, Raman, in-silico modeling for biologics characterizations.
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Required skills: Design bioreactor scale-up strategy; research and develop viral vector process; plan and define tech transfer activities such as bill of materials, protocol transfer process, and gap assessment; multi-scale bioreactor hands-on experience 0.5L - 1000L; analyze process analytical technology (PAT) trends and implementation; Raman, Aber probe, etc.
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Advanced technical skills in solid state characterization of drug substance/intermediates/final product functionality (e.g. Rheology, XRPD, TGA, DSC, DVS, BET, IR, Raman, microscopy, particle size analysis, etc.
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Knowledge and the ability to interpret and draw conclusions from data from common analytical techniques such as dissolution testing, hardness testing, HPLC, XRPD, IR/Raman spectroscopy and particle size analysis techniques.
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Spectroscopic method development (NIR, Mid-IR, Raman, laser diffraction, acoustics) Spectroscopic method development (NIR, Mid-IR, Raman, laser diffraction, acoustics) Knowledge of cGMP's and associated CMC regulatory considerations in a pharmaceutical environment.
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Design and implement new features for Android applications running on X-ray (XRF), laser (LIBS, Raman), and infrared (NIR) portable scientific analyzers. Familiarity with analytical chemistry technologies including XRF, LIBS, NIR, and Raman.
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SIM, QPM and Fourier Ptychography); 2) label-free methods (e.g. FLIM, hyperspectral imaging and Raman; 3) hardware designed for ultra-fast and ultra-high-throughput imaging (e.g. printable micro-lenses and complex light-guides, optimized stages, hardware triggers, exposures, etc.
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The candidate will assist senior staff in developing and performing analyses of a wide variety of materials using a variety of techniques including FTIR, Raman, UV-VIS, GC-MS, LC-MS, DSC. The candidate will assist senior staff in developing and performing analyses of a wide variety of materials using a variety of techniques including FTIR, Raman, UV-VIS, GC-MS, LC-MS, DSC.
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Analysis of chemical data (including, but not limited to NMR, FTIR, Raman, GPC, etc.) As a Polymer Scientist at Axoft, you will work alongside research scientists on polymer synthesis, coating techniques for microfabricated devices and analyze in vitro and in vivo biocompatibility assays.
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Characterize material microstructure including composition, phase, and grain information utilizing techniques like x-ray diffraction, scanning electron microscopy, energy dispersive spectroscopy (XRD, SEM, EDS), and Raman spectroscopy.
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Rigaku is a world leader in X-ray diffraction (XRD), scattering, fluorescence, imaging analyses, Raman spectroscopy, and thermal analysis equipment manufacturing. Rigaku is a world leader in X-ray diffraction (XRD), scattering, fluorescence, imaging analyses, Raman spectroscopy, and thermal analysis equipment manufacturing.
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Demonstrated ability to work in a chemistry laboratory with minimal supervision and familiarity with analytical techniques such as NMR, HPLC, MS, IR, Raman, etc. Bachelor degree in organic chemistry or biochemistry/chemical biology with undergraduate research experience in synthetic methodology, total synthesis, peptide/protein chemistry, oligonucleotide chemistry, or synthetic/conjugation chemistry.
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