Vice President of Global Supply Chain

Position OverviewWe are seeking a strategic and execution-oriented Vice President of Global Supply & External Manufacturing to lead the development and scaling of our end-to-end supply chain and external manufacturing network. This individual will be responsible for ensuring reliable, compliant, and cost-effective supply across clinical and commercial programs, spanning multiple therapeutic modalities.The VP will play a critical leadership role in building and managing a global network of CDMOs, driving tech transfer and commercialization readiness, and partnering cross-functionally with CMC, Quality, Regulatory, and Clinical Operations to support the advancement of our pipeline.Key ResponsibilitiesGlobal Supply StrategyDefine and execute the global supply chain strategy across clinical and commercial stagesEstablish scalable supply models to support pipeline growth and product launchesLead S&OP processes, demand planning, and inventory strategies across regionsExternal Manufacturing LeadershipBuild and oversee a global network of CDMOs for drug substance, drug product, and fill-finish operationsLead CDMO selection, qualification, contracting, and ongoing performance managementEstablish governance frameworks, KPIs, and business review processes with external partnersTech Transfer & Scale-UpOversee all technology transfer activities from internal development to external manufacturing partnersEnsure successful scale-up from early clinical through commercial productionDrive process robustness, reproducibility, and manufacturing readinessClinical & Commercial SupplyEnsure uninterrupted supply of clinical trial materials globallyLead commercialization readiness efforts, including launch supply planning and distribution strategyDevelop supply continuity and risk mitigation plans, including dual sourcing strategiesRegulatory & Quality AlignmentPartner closely with Quality and Regulatory teams to ensure compliance with FDA, EMA, and global health authoritiesSupport CMC sections of regulatory filings (IND, BLA, MAA)Ensure inspection readiness across all external manufacturing sitesFinancial & Operational ExcellenceOwn and manage supply chain and external manufacturing budgetsDrive cost of goods optimization and long-term cost reduction strategiesLead contract negotiations and manage multimillion-dollar CDMO agreementsLeadership & Cross-Functional CollaborationBuild, lead, and develop a high-performing global team across supply chain and external manufacturingServe as a key member of the Technical Operations leadership teamCollaborate cross-functionally with CMC, Clinical, Commercial, and Finance to align on program prioritiesQualificationsRequiredBachelor’s degree in Engineering, Life Sciences, or related field; advanced degree preferred15+ years of experience in biopharmaceutical manufacturing, supply chain, or technical operationsSignificant leadership experience in external manufacturing and CDMO managementProven track record supporting products from early development through commercializationDeep understanding of global regulatory requirements and GxP complianceExperience managing global supply chains across multiple regionsDemonstrated ability to lead large, cross-functional teams and influence at the executive level