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They will gain an understanding of protein expression systems, protein structure and purification and how amino acid variation impacts reactivity with antibodies. For this research project, under the guidance of a mentor, the participant will use a large set of reagents (monoclonal antibodies, and polyclonal sera) and different protein expression approaches to assess antibody responses, define epitopes and understand the rules of antibody immunodominance from two distinct highly diverse RNA viruses, hepatitis C virus and norovirus.
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2+ years of hands-on, laboratory experience in cell analysis, protein biochemistry, immunology, drug discovery/molecular pharmacology, or related field is required. 2-5 years of hands-on, laboratory experience in cell analysis, protein biochemistry, immunology, drug discovery/molecular pharmacology, or related field is required.
$110,000 - $115,000 a yearFull-timeExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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Degree in biology, biochemistry, chemistry, immunology, organic chemistry, or protein engineering, or related discipline. Degree in biology, biochemistry, chemistry, immunology, organic chemistry, or protein engineering, or related discipline.
$225,000 - $250,000 a yearFull-timeExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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Candidates may be considered with a broad range of CMC experience to include cell line development, cell culture, purification, analytical development and characterization, formulation development, and/or drug product manufacturing.
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Dive into the world of water purification solutions and make a splash with your sales expertise! Carry out persuasive demonstrations tailored to homeowners, highlighting the benefits of our water purification solutions.
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Due to our growth and the launch of new products, we are seeking a highly motivated individual to join a team of researchers, engineers, and scientists as a remote Field Application Scientist based in our Mid Atlantic territory.
$100,000 - $115,000 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Background in biology, biochemistry, chemistry, immunology, organic chemistry, or protein engineering required. Background in biology, biochemistry, chemistry, immunology, organic chemistry, or protein engineering required.
$225,000 - $250,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Perform biochemical assays, protein expression and purification, assess sample quality, prepare samples for analytical studies included but no limited to spectroscopy (absorption, fluorescence, circular dichroism), determine binding constants by various methods (spectroscopic, analytical centrifugation, size-exclusion chromatography, SEC-MALS, DLS and related.
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Collects and interprets data for biomarker and biological characterization assays including cell-based, multiplexed protein assays, polymerase chain reaction and flow cytometry methods. Runs RNA and protein assays with necessary troubleshooting.
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Water purification systems, and oversee the activities of lifeguarding staff. Maintains swimming pool water quality by testing hourly and cleaning pool components weekly. Maintains swimming pool water quality by testing weekly and cleaning pool components.
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Conduct research on projects associated with antimicrobial development such as protein expression and purification, MIC (minimum inhibitory concentration) studies, animal modeling, virtual modeling of drugs bound to target proteins, etc.
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Perform routine experiments and tests, including tissue culture, cell separation, protein, and quantitative and qualitative analysis. Plan and execute experiments for in vitro and in vivo studies, including cell culture, Western blotting, and immunofluorescence/immunohistochemistry.
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The dedicated units provide expertise in electron microscopy, protein characterization, mass spectrometry, protein expression, optical microscopy, and genomics. The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.
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Perform quantitative analytical assessments of changes in molecular and cellular mediators underlying responses to stressors, injury, and countermeasures to these disruptions using histopathological, biomedical, and molecular techniques such as immunohistochemistry, proteomics, lipidomics, analyses of mRNA, miRNA, and micro array protein analysis, bioenergetic profiling, quantitative Polymerase Chain Reaction (PCR), Western blot, multiplex assays, and Enzyme Linked Immunosorbent Assay (ELISA.
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Experience with microbiology of Gram-negative negative species, antibacterial development, genetics and molecular cloning to determine and develop target antigens, eukaryotic cell culture, expression vector design, transient transfection, recombinant antibody testing and development, protein expression.
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protein purification jobs in Washington, DC
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