Software Engineer II

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. As a Software Engineer II specializing in AkesoLIMS at Tempus, you will contribute to the design, development, and maintenance of our Laboratory Information Management System. In this role, you will build and enhance software that supports laboratory operations, data management, workflow execution, and REST API development across both backend and frontend systems. You will work closely with Laboratory staff and Project Management to gather requirements, translate laboratory workflows into technical solutions, and deliver reliable, scalable applications that improve efficiency and usability for end users. Why we’re looking for you (required skills) You have strong experience with C# and application development using ASP.NET and MVC. You have experience developing REST APIs in C#, Python, or Node.js. You have strong SQL Server skills and are comfortable writing, optimizing, and troubleshooting SQL queries and database objects. You have front-end development experience using JavaScript and jQuery. You have experience using AI-assisted development tools such as GitHub Copilot, Cursor, and Claude to improve productivity, accelerate learning, and support software delivery. You are comfortable contributing across both backend and frontend development. You can work directly with Laboratory staff and Project Management to gather, clarify, and refine requirements. You are able to translate operational and user needs into practical software solutions. You’ve worked in collaborative environments and are comfortable iterating on features and enhancements with cross-functional partners. You embrace GenAI tools in your day-to-day work to boost productivity, accelerate learning, and focus your energy on solving the most impactful problems. Bonus points for Knowledge of laboratory workflows. Experience working with LIMS platforms or laboratory information systems. Experience with Python. Familiarity with Google Cloud Platform (GCP) environments. Experience with additional AI tools for software development and prototyping. Key Responsibilities Design, develop, test, and maintain features for AkesoLIMS. Build and support software across both the backend and frontend application stack. Develop solutions using ASP.NET, MVC, C#, JavaScript, and jQuery. Design, develop, and maintain REST APIs to support system integrations and application functionality. Use AI-assisted engineering tools such as GitHub Copilot, Cursor, and Claude appropriately to improve development efficiency, code quality, and documentation. Design and optimize database interactions in SQL Server. Partner with Laboratory staff to understand workflows, pain points, and process requirements. Collaborate with Project Management to define scope, requirements, priorities, and delivery plans. Troubleshoot defects, support production issues, and improve system reliability and performance. Contribute to technical documentation, code reviews, and development best practices. Technical Environment Backend: ASP.NET, MVC, C#, REST APIs Frontend: JavaScript, jQuery Database: SQL Server AI Tools: GitHub Copilot, Cursor, Claude Nice to have: Python, Node.js, GCP #LI-Hybrid #LI-HR1 We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. About Us Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics. We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives. Why Work Here? We’re looking for people who can change the world. Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.