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SeniorScientistAutomation and Advanced Modeling

BiospaceSomerville, MAApril 22nd, 2026
Job title: Senior Scientist Automation and Advanced ModelingLocation: Cambridge, MAAbout The JobWe areseekinghighly motivatedindividualto join ourdrug substance process engineering and modelingteam. As a technical expert inprocess engineering and modeling, you will play a key role in advancing our global engineering department within Sanofis R&D CMC Synthetic organization.This positionis located inCambridge MA andwill collaborate closely with colleagues in France to support digital development andimplement new ways of working.Yourexpertisein chemical engineering, process system modeling, and lab automation will be crucial in creating a self-driving lab for small molecule drug substanceprocessdevelopmentand optimization.You will helpdevelopingautomated experimental workflows to generate data for model building, advancing the creation of digitaltwinsand driving innovation in pharmaceutical process development.We believe that lab automation and digital development are crucial for the future of process development in Pharma. By joining our team, you will be at the forefront of this transformation, using yourexpertiseto push the boundaries of process engineering.This is an exciting opportunity todemonstratethe benefits of process modelling and data science in a cutting-edge scientific department developing the next generation of Sanofi medicines that will improve the quality of life for patients across the world.Join the engine of Sanofis mission where deep immunoscience meets bold, AI-powered research. In R&D, youll drive breakthroughs that could turn the impossible into possible for millions.About SanofiWere an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve peoples lives.Main ResponsibilitiesLab automation &data generation:You will work closely with laboratory teams (process chemists, engineers, and the high-throughput experimentation team), fostering strong partnerships with scientists to deeply understand their research processes. Your goal will be to design, develop, and deploycutting-edgeautomated systems, robotics, instrumentation, and digital workflows that significantly enhance the productivity and efficiency of our labs.Youwillbe responsible forprogramming and developing automated laboratory systems. This includes supporting software development and deployment to automate workflows, integrating analytical instruments with laboratory software, and ensuring seamlesscommunication between instruments and Sanofi's internal data management services.Mechanistic &data-drivenmodel BuildingAs part of matrix project teams, build mechanistic, hybrid, and data-driven modeling solutions to support small molecule process development.Collaborate with process development teams to integrate crystallization modeling into the overall process design and optimization workflow.Model Deployment At ScaleAssist in the development and deployment of digital twins for both batch and continuous processes, ensuring alignment with Quality by Design (QbD) principles. You will play a key role in implementing and scaling Model Predictive Control (MPC) systems,leveragingadvanced process models tooptimizeperformance in real-time,maintainproduct quality, and enhance operational efficiency across large-scale manufacturing environments.Provide concise technical presentations to communicate work to project teams, cross functionalteamsand management.Document all work on projects and continuous improvements ineLNBexperiments and summarize in Technical Reports.Establish/extend externalnetworkby providing leadership on academic, industrial, or government sponsored collaborations.Steer collaboration projects to address gaps in scientific knowledge.About YouPhD inchemical engineering, mathematics or physicsand OR a masters degree inchemical engineering, mathematics or physicsand with a minimum of4 years ofexperienceOR a bachelors degree inchemical engineering, mathematics or physicsand with a minimum of 8years experience.Strong skills in writing andoptimizingscripts in programming languages such as Python/Matlab/C#/Visual Basic.Experience in designing and implementing automated laboratory processes from theinitialconcept through to full deployment.Demonstrated ability to translate mathematical models into computer programs.Preferred QualificationsExperience with crystallization modeling and simulation tools (e.g.,gPROMS).Familiarity with laboratory analytical measurement instruments or relevant work experience in a pharmaceutical sciences laboratory setting.Domain knowledge in small molecule process development withdemonstratedindustrial applications or academic publications in this fieldSome knowledge in Multivariate Analysis,chemometricsand statistics.Experience in the development and scale-up of continuous processes.Soft SkillsAn ability to work as part of a team, engaging other scientists with complementary skill sets in the field of pharmaceutical development.A change agent mentality, proposing novel approach to challenging scientific questions and exploring new modeling approaches.Why Choose UsBring the miracles of science to life alongside a supportive, future-focused team.Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave.Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.Help improve the lives of millions of people globally by making drug development quicker and more effective.Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.#GD-SA#vhdAll compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.