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Strong knowledge and agility in study design and data interpretation and in the integration of Toxicology studies in the drug progression paradigm, as well as in the incorporation of safety endpoints in pharmacology studies.
$265,200 - $439,300 a yearFull-timeExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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Reporting to the VP and Head of Research, the Senior Director, Integrative Biology will be the senior in vivo scientist in the pre-clinical research organization overseeing pharmacology and toxicology experiments.
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Support preclinical formulation delivery for PK, pharmacology, and toxicology studies to achieve the desired PK coverage in preclinical studies. Ph. D in Pharmaceutical Science, Chemistry, Chemical Engineering, or related discipline with 3+ years or BS/MS with 7+ years industry experience in pharmaceutical preclinical formulation development.
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Experience as Non-Clinical Operations Manager in Pharmacology, DMPK and/or Toxicology. The Non-Clinical Operations Manager will support all nonclinical activities in Pharmacology, DMPK and Toxicology functions for Olema Oncology ranging from early candidate nomination, IND/CTenabling, and NDA/MAsupporting studies.
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Understanding of the related disciplines (i.e. biostatistics, regulatory, pharmacology and toxicology research, cell therapy manufacturing, clinical pharmacology and pharmaceutical sciences.
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Serve as Safety Assessment (Toxicology/Pathology), DMPK, Clinical Pharmacology, Biomarker, and Bioanalytical function interface between Denali and external CRO collaborators, developing productive relationships and leading efforts to achieve optimal efficiency in external workflows and ensuring compliance GLP, GCP and GCLP regulations.
$170,000 - $202,000 a yearFull-timeExpandUpdated Today - UpvoteDownvoteShare Job
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Represent and provide clinical pharmacology expertise and leadership at cross-functional development project team, clinical subteam, study team, partnering with clinical research, biometrics, project management, clinical operations, drug metabolism, biology/biomarkers, toxicology etc.
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PKDM works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to design promising clinical therapeutic candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.
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Understanding and application of the pharmacology, chemistry and non-clinical toxicology to effectively conduct safety surveillance. The PST lead will also closely collaborate with a PK and toxicology leads to help guide dose selection and regimen, inclusion/exclusion criteria and safety monitoring for first in human and phase I/II studies.
Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Strong knowledge of a broad range of nonclinical studies relevant to drug development (Toxicology, DMPK, Bioanalytical, Biology, Pharmacology). Clinical Pharmacology and biomarker experience preferred.
$240,000 - $300,000 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Review, maintain and update databases for DMPK, Pharmacology and Toxicology data. This role reports to the Vice President of Non-Clinical Pharmacology and Toxicology. Serve as liaison between Research and CMC groups to ensure Certificates of Analysis and stability for toxicology lots is maintained and represent Research in periodic stability updates.
ExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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This position reports to the head of clinical pharmacology and DMPK and liaises with clinical development, clinical operations, non-clinical pharmacology and toxicology, and drug discovery to execute activities for advancing the development pipeline.
$198,000 - $220,000 a yearExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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Serve as a QTAS representative on project teams supporting the development of novel biologics; collaborate with project team members (e.g., clinical pharmacology, protein analytics, discovery, toxicology) and groups within QTAS to generate relevant data guiding target validation, biomarker selection, and candidate selection.
ExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Bachelors (BS/BA) in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related discipline is required; The Investigative Toxicology group’s goal is to use ex vivo and in vitro tools to assess safety liabilities and mechanisms of toxicities observed pre-clinically to support the entire portfolio spanning discovery through development.
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Candidate will provide scientific and technical support to assays and platforms supported by the Investigative Toxicology group by: Performing experiments involving: immortalized and primary cell culture, cell viability assessment, Luminex/ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry.
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pharmacology toxicology jobs in South San Francisco, CA
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