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The Amgen Translational Immunology and Safety Sciences group based in South San Francisco, CA, is seeking a Principal Scientist to independently investigate immune related safety assessment with in vitro approaches and provide immuno-toxicological evaluation strategy to support Inflammation pipeline projects.
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Duties in San Francisco will include performance of cellular immunology assays, mostly based on flow cytometry (Cytek Aurora spectral flow cytometer, FACS ARIA cell sorter, and LSRII cytometers) or ELISpot, development and validation of new flow panels and assays, data management, as well as using software to analyze high parameter flow data.
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Candidates must have expertise in Biology/Immunology, and basic cellular, experience in CRISPR-Cas gene-editing technology, experience in cloning, recombination technology, expression, and functional studies, experience in antibody functional characterization, immune checkpoint functional assays, ligand binding assay, cell-based binding assay, reporter gene assays, cell killing experiments.
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Its mission is to improve the health and well-being of all people through medical research and education in neuroscience, cardiovascular biology, immunology, and stem cell biology. This position represents an excellent opportunity to gain exposure to basic laboratory skills as well as gain exposure to the frontier of cancer immunology and next generation genomics technologies in a dynamic, well-established research environment.
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Coordinates with Cancer Immunology, Protein Chemistry, Antibody Engineering, and Translational Oncology groups to advance lead molecules of the projects. Experience with multi-color flow cytometry, T cell functional assays, ELISA assays, culture of mammalian cell lines and primary immune cells is required.
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PhD in Endocrinology, Physiology, Diabetes/Obesity, Immunology/Inflammation, or a related biological science (MS with relevant years of experience). Experience with therapeutics programs that have yielded drugs entering clinical development in areas such as endocrinology, diabetes/obesity, immunology/inflammation, or metabolic disease.
$170,000 - $200,000 a yearFull-timeExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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Your direct supervisor will be Dr. Marlys Fassett, a physician-scientist/dermatologist whose research program spans from in vitro molecular immunology to neuroimmunology to mouse models of inflammatory disease.
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At DICE Therapeutics, a wholly owned subsidiary of Eli Lilly & Company, we design and develop innovative therapies in immunology for patients with debilitating disease. Responsibilities:We are currently seeking a Director, Drug Metabolism and Pharmacokinetics, who will have scientific oversight of one or more of the small molecule discovery projects and will manage the in vitro and in vivo PK, ADME and bioanalytical assays.
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The Principal Scientist Pharmacology role will be in the Biomarkers & Immunology group. This role will report to the Senior Director of Biomarkers & Immunology and be part of a talented, motivated, and creative team of scientists who are critical for the success of 4DMT's mission and development of our deep portfolio of targeted genetic medicines.
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The ideal candidate will contribute to our goals of navigating what’s next in synthetic biology, immunology and cell engineering while living our core values: Bring Intellectual Rigor, Elevate Each Other, and Stay True To Why.
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Founded in 2021, Shennon Biotechnologies is focused on leveraging microfluidics, cancer genomics, and immunology approaches to create a platform for TCR discovery and immune cell profiling to find effective targets forcancer immunotherapy.
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The Department's 18 divisions include Academic General Pediatrics, Child Development & Community Health; Allergy, Immunology, and Rheumatology; Cardiology; Dermatology; Dysmorphology; Emergency Medicine; Endocrinology; Gastroenterology; Genetics; Genome Information Sciences; Hospital Medicine; Infectious Diseases; Neonatology; Nephrology; Pharmacology & Drug Discovery; Rehabilitation Medicine; and Respiratory Medicine.
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The PositionWe are seeking a highly motivated postdoctoral research fellow to join the Turley Lab in the highly collaborative Department of Immunology Discovery at Genentech. Postdoctoral training in human T cell immunology.
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Strategic HR business partner driving the people strategy, workforce planning, organizational design, talent management, team effectiveness and change management for Immunology and Cardiovascular Thematic Research Center and Oncogenesis Thematic Research Center.
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The ideal candidate will contribute to our goals of navigating what's next in synthetic biology, immunology and cell engineering while living our core values: Bring Intellectual Rigor, Elevate Each Other, and Stay True To Why. The successful candidate will join the Process Development - Cell Therapy Group and contribute to the development of genetically modified T cell manufacturing processes and will be responsible for developing the next generation of cell therapy processes.
$140,000 - $185,000 a yearFull-timeExpandApply NowActive JobUpdated Today
toxicologist immunology jobs in San Francisco, CA
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