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Demonstrated experience with routine molecular biology techniques (DNA/RNA/protein isolation, cDNA synthesis, RT-PCR, qPCR, digital PCR, western blot, and immunofluorescence) The Sr. Research Associate will support the Discovery Bioscience team and assist in developing and executing screening assays for the evaluation of AAV vector products.
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Parvus’ leadership team is experienced in successful drug discovery, development, manufacturing, regulatory approval, and commercialization. Primary Responsibilities: Primary contributor with protein characterizing mass spectrometry experiments, including maintaining the instrument, developing and performing experiments with an emphasis on intact mass, glycan analysis and peptide mapping studies.
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The Susa lab is starting the Department of Pharmaceutical Chemistry at UCSF and is seeking applicants for a research technician position using structural biology, membrane protein biochemistry, cell biology, and protein engineering to understand fundamental mechanisms of transmembrane signaling within the human immune system.
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The candidate will utilize molecular, cellular and computational biology, along with state-of-the-art single-cell technologies, to study translational control and protein homeostasis in the context of drug resistance.
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Responsibilities:We are currently seeking a Director, Drug Metabolism and Pharmacokinetics, who will have scientific oversight of one or more of the small molecule discovery projects and will manage the in vitro and in vivo PK, ADME and bioanalytical assays.
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B.S. or M.S. with 2+ years of relevant research experience, preferably in drug discovery in pharmaceutical or biotechnology industry. · Attention to detail and enthusiasm for integrating basic science learning with drug discovery efforts.
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The PositionThe PositionThe Department of Physiological Chemistry at Genentech is seeking a talented and motivated protein biochemist to drive structure-function studies of challenging membrane proteins involved in cell death and inflammation.
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The Biologics Drug Product Development department is within the AbbVie Bay Area (ABA) Chemistry, Manufacturing, and Controls (CMC) Biologics department in South San Francisco, CA. This group is responsible for formulation and drug product process development that are required for developing stable and fit-for-purpose biologic drug products.
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Skills: Molecular Biology, Cell Biology, Biology, Chemistry, Chromatography, Protein Purification, Cell Cultures, Manufacturing Operations. Experience in cell culture and/or protein purification.
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Nobell is seeking a Computational Biologist / Machine Learning Scientist to join our team of scientists to contribute to the development of the Nobell Plant Grown Protein (PGP) platform. Develop and implement algorithms across a range of in-house acquired data including, but not limited to genetic sequences, RNA expression, protein expression and protein structure.
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This role will support chromatography assay development for monoclonal antibodies, bispecific antibodies, cytokines, and antibody drug conjugates. PhD in analytical chemistry, biochemistry, molecular biology or related scientific field and 2+ years of industry experience in the characterization of large molecule biologics is required OR.
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Junior or Assistant Specialist (Protein Biochemistry) - Kortemme Lab. One year or more of research experience in protein biochemistry or high-throughput technology in academia or industry.
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PhD in Analytical Chemistry, Biochemistry, or Biotechnology and successful postdoctoral research training in a related field Minimum of 6 years of hands-on experience with liquid chromatography and tandem mass spectrometry (LC-MS/MS) approaches, and have excellent troubleshooting capabilities.
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Strong understanding of drug discovery and development processes, including preclinical, clinical, and regulatory requirements. CytomX has a broad pipeline, which comprises seven therapeutic candidates across multiple treatment modalities including antibody-drug conjugates ("ADCs"), T-cell engaging bispecific antibodies ("TCBs"), and immune modulators such as cytokines and checkpoint inhibitors ("CPIs.
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Quantitative Systems Pharmacology (QSP) & Physiologically Based Pharmacokinetics (PBPK) have become important components of discovery and clinical development. Assist therapeutic area expert modelers to accelerate efforts and ensure timely model development and calibration to impact drug development programs and coordinate technology development.
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protein chemistry drug discovery jobs in San Francisco, CA
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