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Other responsibilities may include utilizing nonclinical PK and PK/PD data (including use of modeling and simulation techniques) to project optimal clinical dosing regimens, doses based on pharmacological/clinical targets, human starting doses, and biomarker exploratory data (including biochemical and molecular data from quantification of mRNA, multi-panel flow cytometry, and protein expression)This position is Hybrid based and travel to our San Francisco office on a regular basis.
$239,000 a yearFull-timeExpandApply NowActive JobUpdated 27 days ago - UpvoteDownvoteShare Job
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Expertise in independently leading lab-based research projects involving a wide repertoire of experimental techniques such as conventional/spectral flow cytometry, biochemistry, cell/molecular biology, and immune function assays.
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Experience in, and deep technical understanding of, preclinical and clinical sample collection/processing and cellular/molecular lab techniques such as cell culture, primary cell isolation from tissues, immunostaining, molecular biology, ELISA, western blot, flow cytometry, genomic sequencing, qRT-PCR, and/or transcriptomics is required.
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Prior experience with human tissue culture and organoid culture and flow cytometry is a plus. Prior experience with human tissue culture and organoid culture and flow cytometry is a plus.
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In vitro work includes a range of cellular assays, cell culture including multiparametric flow cytometry and molecular biology techniques to help interpret in vivo observations. skills: Molecular Biology, Cell Biology, Biology, GLP (Good Laboratory Practice), In Vivo, Flow Cytometry.
$30 - $36.05 an hourFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Duration: 12 monthsLocation: South San Francisco, CAAs a Scientific Researcher I, you will be:Job Description:The Scientific Researcher performs laboratory-based activities and processes related to the tracking registration inventory preparation e.g. DNA/RNA extractions from human biospecimens fluid and tissue samples human cell culture organoid culture Serum Plasma and PBMC isolation from blood samples and distribution of biological samples from clinical and non-clinical trials.
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Proficiency with stable cell line development, preferably in CHO cells, including transfections, selections, subcloning, flow cytometry, protein measurement by Octet and HPLC. Proficiency with molecular biology techniques including molecular cloning; preparative and analytical DNA/RNA PCR/qPCR/RT-PCR; proficiency with associated software, ex Geneious, Sequencher.
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This role involves overseeing transfection and mammalian cell culture processes, conducting cloning, screening, and flow cytometry, and collaborating closely with both internal teams and external partners.
$175,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Contribute to the project development and perform cellular immunological techniques including multi-color flow cytometry, ELISA, MSD, in vitro and ex vivo immune cell assays. Experience with multi-color flow cytometry for immune cell profiling is required.
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The Scientific Researcher performs laboratory-based activities and processes related to the tracking, registration, inventory, preparation (e.g., DNA/RNA extractions from human bio specimens (fluid and tissue samples), human cell culture, organoid culture, Serum, Plasma and PBMC isolation from blood samples) and distribution of biological samples from clinical and non-clinical trials.
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Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits. Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits.
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PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with minimum of 2 years of post-graduate experience (preferably in industry), MS with 8+ years of research experience, BS with 10+ years of research experience in antibody or protein engineering.
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Reporting to the Cell Therapy lead for our first LINK program, the successful applicant will be part of a team that is characterizing and optimizing one of the company’s core platforms: Logic-gated Intracellular Network (LINK) CAR. Within this role, they will work on understanding core biology of the platform with viral generation, transduction of human T cells, and functional assays involving cytotoxicity, flow cytometry, and long-term persistence.
$145,000 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Responsibilities include culturing and maintaining human cell culture lines, performing flow cytometry and microscopy, performing standard molecular biology techniques, implementing automation protocols, performing basic statistical calculations, and other duties as assigned.
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Ability to analyze and interpret complex, high dimensional datasets including those generated by flow cytometry, next-generation sequencing (NGS), epigenetic analysis and / or proteomics in collaboration with bioinformatics colleagues.
Full-timeExpandApply NowActive JobUpdated 3 days ago
flow cytometry jobs in San Francisco, CA
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