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You have insatiable curiosity, including for understanding the role of generative AI, machine learning (and other computational approaches), and data at scale to transform drug discovery and development.
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Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV‐Vis. Bio-conjugation experience, protein biochemistry and Chemistry background Must be team player, adheres to timeline, communicative and collaborative.
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About Charles River Cell Solutions Charles River Cell Solutions is a global leader and trusted brand in the customization of human-derived biological products and services for biomedical research, drug discovery, and cell and gene therapy development.
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Working with a team of interdisciplinary data scientists, engineers, architects, and consultants, our work includes novel areas such as cancer detection, drug discovery, optimizing population health and clinical trials, autonomous systems and edge AI, and renewable energy.
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Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science, and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.
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Bexotegrast has received Fast Track Designation and Orphan Drug Designation from the U.S. Food and Drug Administration for both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC) and Orphan Drug Designation from the European Medicines Agency in IPF and PSC. Pliant is currently conducting BEACON-IPF, a Phase 2b/3 trial of bexotegrast for the treatment of IPF.
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The Associate Director of Radiopharmaceutical Process Development will be executing the CMC development plan and IND enabling activities, leading to the clinical manufacturing of the Drug Product.
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Responsibilities:We are currently seeking a Director, Drug Metabolism and Pharmacokinetics, who will have scientific oversight of one or more of the small molecule discovery projects and will manage the in vitro and in vivo PK, ADME and bioanalytical assays.
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In this role you will be responsible for developing assays for the GMP release of drug substances and drug products, using HPLC, Capillary Electrophoresis, AUC and Mass Spectrometry.
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The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents.
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Education and Knowledge, Skills and Abilities Required: Registration or Certification with Drug and Alcohol Certification recognized by ADP. 1 year or more experience working in a childcare environment or bachelor's degree in early childhood development.
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This role offers strategic statistical input for drug development planning, including feasibility assessments, study design, statistical methodologies, data interpretation, and regulatory submissions (IND, NDA, MAA, etc.
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At least three (3) years of progressively responsible work or volunteer experience in a community-based health care or social work setting or at least one (1) year of experience as either a Case Manager II or Case Manager III or equivalent position or registration or certification as a Certified Alcohol and Drug Counselor by one of the two certifying bodies in California.
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By collaborating closely with biologists, biophysicists, chemists, and structural biologists you will uncover fundamental biology to advance our efforts in drug discovery, and help to develop Lyterian’s computational biology strategy across functions.
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Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. At least 10 years plus experience of clinical drug development in pharmaceuticals/biotech industry, including designing and implementation of clinical trials in early/late stage.
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