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This scientist will be responsible for design and development of ddPCR assays, quantitating DNA and mRNA both in vitro and from in vivo samples. Depending on experience, the scientist will expand molecular and product specific assay development working with the analytical development team.
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We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead discovery, in vivo pharmacology, as well as other research and development services.
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Responsible for the development and execution of in vitro or ex vivo assays to characterize receptor binding, signaling, cell activation/suppression, and other functional readouts using a variety of techniques including flow cytometry-based assays, ELISA, and reporter assays.
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These include intellectual input and decision-making on protein targets to be pursued, development of immunogens and immunization strategies, utilization of hybridoma technology, and antibody validation in vitro and in vivo.
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Extensive knowledge of cell therapy concepts and exploration, including in vitro and in vivo study experience. Design and perform a variety of in vitro, ex vivo and in vivo experiments spanning multiple programs to assess cell therapy products’ function and potential efficacy: average expected time at the bench 70.
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In vivo expertise including animal handling, blood collection (cheek bleeds/cardiac sticks), IV dosing, necropsy, tissue dissections, tumor implants and measurement) · Execute in vivo mouse studies using methods including, but not limited to subcutaneous tumor inoculation, intravenous tail vein injections, weighing animals, measuring tumor size, collecting blood samples via cheek bleeds/cardiac puncture, and harvesting tissues.
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Senior Scientist/Principal Scientist, Formulation and Process Development. We are currently searching for a highly motivated and innovative Formulation Scientist to join our Formulation/Process Development team.
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Successful candidates should have a PHD, MD, or equivalent degree with training in Molecular Biology, Genetics, Developmental Biology, Bioinformatics, Stem Cell Biology, immunology, mouse work, mouse genetics, and mammalian cell culture.
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Identify CROs with suitable animal models to demonstrate in vivo PD and efficacy of compounds. PhD in Immunology or a related field. We raised in August 2023, and have raised over $280M in funding from top technology and biotech investors, including Andreessen Horowitz, Rock Springs Capital, T. Rowe Price, Fidelity, Radical Ventures, NVentures (NVIDIA's VC arm), BlackRock, and Menlo Ventures.
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Performs assigned experiments to support scientific activities and project goals involving in vivo pharmacology assessment of novel therapeutics. Independently execute in vivo PK/PD and/or efficacy studies that support nonclinical and clinical stage programs in the neuropsychiatry, neurology, and neuroendocrinology disease space.
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For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology, and children’s diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities.
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Meet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development! Meet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development.
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We are looking for a thoughtful and creative Battery Scientist, with strong hands-on experience and excellent attention to detail to join our team in the Bay Park area of San Diego, CA. The ideal candidate would be given a target and independently design research plans and work with a team to perform experiments, analyze data, and recommend new pathways.
$100,000 - $170,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Design and implement experiments for the formulation and characterization of polymeric, liposomal, lipid and other nanoparticles for in vivo drug delivery. Design and implement experiments for the formulation and characterization of polymeric, liposomal, lipid and other nanoparticles for in vivo drug delivery.
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Hands-on experience with ex vivo analysis employing contemporary cellular, molecular, and immunological techniques such as PCR or NanoString, flow cytometry, and protein analysis by Western/MSD/ELISA etc.
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scientist immunology vivo jobs in San Diego, CA
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