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Candidates should have a demonstrated record of excellent competency in laboratory research, with a focus on protein-related work, molecular biology, cell biology, and/or immunology, and should have a strong understanding of mammalian cell biology, biochemistry and chemical biology, and immuno-oncology.
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Education requirements include master’s of science with specific focus in one or more of the following disciplines: cell signaling, cell physiology, protein biochemistry, cancer biology and immunology.
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Previous experience in cell culture scale-up, tech transfer including drafting development reports, production batch records, protocols and Knowledge of scale-up and scale-down models is highly desired.
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Based in San Diego, Poseida Therapeutics is a clinical-stage biopharmaceutical company utilizing our unique and proprietary genetic engineering platform technologies to create next-generation cell and gene therapies with the capacity to cure.
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Using advances in genomic sequencing, the human microbiome, metabolomics, informatics, computing, and cell therapy technologies, HLI is building the world's most comprehensive knowledge base of human genotypes and phenotypes as a basis for a variety of opportunities to help solve aging related disease and human biological decline.
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A key focus of this role will be to design and execute integrative analyses that leverage cutting edge single cell-level assays including 10x, CyTOF, spatial-omics and CRIPR-seq screens to prioritize disease mechanisms, prioritize targets, and discriminate between disease subtypes.
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Tentarix's Cell Biology team is seeking a highly motivated and outstanding Senior Scientist to lead discovery efforts in building and executing on multifunctional biologics for oncology and autoimmune indications.
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Experience working with trauma patient, cardiac devices and with Rapid Infusion Devices and Blood Salvaging Devices (Cell Saver) used in procedures. Operates rapid infusion devices and cell saver devices in operating room.
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Strong experience in cell-based assay development and mechanistic target biology research. PhD in Chemical Biology, Molecular/Cell Biology, or Biochemistry or related field with 3+ years of biopharmaceutical industry research experience.
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Cedars-Sinai, a world-class healthcare organization, is seeking a highly skilled and dedicated Nurse Practitioner (NP) to join our Cardiac Surgery team. Our faculty and attending physicians provide deep competency across all specialties, including transplantation, stem cell therapy, congenital heart disease, women's heart health, valve disorders, arrhythmia, and hypertension.
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Good knowledge of cell-based methods associated with bioanalytical analytical method development (e.g. TCID50, Potency assay, viral transduction, and ELISA methods) preferred. Familiar knowledge of GLP and GMP requirements as they pertain to protein and gene therapy process development and Quality Control (QC) testing is a plus.
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Deep understanding of NGS-based assay development processes, algorithms, and workflows, including those related to microbial, RNASeq, and single-cell multi-omics applications. Provides bioinformatics and data science subject matter expertise in the planning and execution of cell and gene therapy projects that require advanced analytics methods, ensuring the maximum value is realized for data generated.
$190,000 - $257,500 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Prior experience and a high degree of proficiency with the following techniques are required: cell culture, transfection, RNA isolation, quantitative RT-qPCR analysis, Western Blot, processing of animal tissues.
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Degradation of SMARCA2 in tumor cells with a SMARCA4 loss-of-function (LoF) mutation results in cell death. The company is powered by its proprietary TPD drug discovery platform , which integrates degrader chemistry design principles and screening libraries with cell-based, target-specific degradation assays, including an ultra-high-throughput screening platform, to enable the identification of drug-like, cell-permeable degrader molecules.
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High-level capability with mammalian tissue culture, primary T-cell culture, and viral vector production. The Scientist I/II will work with Tr1X’s Virology/Molecular Biology team to design and execute studies in cell lines and primary immune cells to characterize candidate viral vectors and processes to support pipeline program advancement.
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