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Design, synthesize and characterize peptides, small proteins and chemically-modified analogs using state-of-the-art synthesis, bioconjugation, purification, analytical and biophysical techniques.
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We specialize in analytical chemistry, drug discovery and development, life science, and toxicology applications with a particular emphasis on Mass Spectrometry, LCMS, GCMS, HPLC, FPLC, liquid handling, and automation.
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Fast-paced and collaborative environment as an Associate Scientist within the Analytical and Formulation group of Avidity’s Chemistry, Manufacturing and Controls (CMC) department. a hands-on presence in the laboratory and support biology and chemistry departments with analytical and biophysical characterization as needed.
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Experienced in bioconjugation chemistry and downstream purification processes, with hands-on experience in the generation and characterization of bioconjugates. Design and execute laboratory experiments to optimize and characterize conjugation chemistries and downstream purification processes for peptide-based bioconjugates.
$106,400 - $154,325 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Basic tissue culture and purification responsibilities include performing cell culture work, antibody purification, conjugation, and associated quality control steps including purity analysis, isotype testing, mycoplasma detection, and specificity measurement by assigned methods.
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Experience with diverse purification approaches for different antibody formats, analytical characterization (SEC-HPLC, cGE, mass spec, cIEF, SEC-MALS), and developability assessment (thermal stability, poly specificity, hydrophobicity, forced degradation, serum stability) is required.
Full-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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The advanced bio & physical sciences for low carbon energy team is the central research organisation for biosciences, chemistry, materials sciences, fundamental biofuels pathways, green hydrogen/ electrochemistry, and the science of carbon capture.
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Execution of more advanced analytical techniques with assistance such as PXRD (X-ray diffraction), DSC (Differential scanning calorimetry), FT-IR (infrared spectroscopy), TGA (thermogravimetric), and SEM (scanning electron microscopy.
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The Research Associate will be responsible for conducting hands-on experiments including but not limited to molecular biology, mammalian cell culture, recombinant protein purification and characterization.
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Expertise in medicinal chemistry principles, cheminformatics, ADME, ML/AI and structure-based drug discovery. PhD in computational chemistry, computational biology, computational chemical biology, or related field.
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The Fleet Solutions group provides turnkey overhaul / repair, testing, and parts sales for air compressors, main propulsion steam turbines, valves, steam turbine generators, auxiliary turbines, dehydrators, pumps, strainers, PLCs, blowers, and water purification.
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Expert proficiency in one or more commercial drug discovery platform such as ICM, Schrödinger, CCG and/or OpenEye. This vital Computer-Aided Drug Discovery (CADD) role, located at our San Diego, CA site, will join our talented and innovative drug discovery team.
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Knowledge of methods for protein purification, conjugation to fluorochrome and haptens, flow cytometry, immunochemical and immunoassay techniques highly desirable. Experience with organic chemistry.
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Must have direct experience with oligo synthesis equipment (e.g., AKTA Oligopilot, AKTA Pilot/Beckman Purification systems, Dionex/Vanquish HPLC analytical systems, rotary evaporators). Bachelors degree or Masters degree in (Bio)chemistry, Chemical Engineering, Microbiology, Biology or related field.
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Experience with T-cell characterization methods (flow cytometry (multiparametric and ICS), cell-based assays (proliferation, cytotoxicity), ELISA, multiplex cytokine assays,purification using MACS system, etc.
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purification analytical chemistry jobs in Coronado, CA
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