Senior Scientist, Advanced MIDD & Quantitative Systems Pharmacology

Contract Duration: 24 monthsPurposeWe are building comprehensive Model-Informed Drug Development (MIDD) capabilities in-house to create reusable platform models across our oncology portfolio. We seek a talented and motivated expert to develop advanced Quantitative Systems Pharmacology (QSP) models in oncology that enable Virtual Population simulations. You will act as a MIDD expert for oncology and integrate this knowledge into Clinical Pharmacology strategy for related development programs.This meansDevelop QSP platform models for multiple oncology mechanisms including: Immune checkpoint inhibitors (IO/ICI) across colorectal, lung, and ovarian cancersAntibody-drug conjugates across lung, ovarian, and colorectal cancersT-cell engagers and bispecifics/trispecifics in multiple myelomaCAR-T therapies in hematologic malignanciesCreate and optimize Virtual Populations to capture patient heterogeneity and support clinical trial designImplement new methods to enhance QSP-driven MIDD, including AI/machine learning augmentation for literature screening, model drafting, and virtual population optimizationDeliver practical results that inform dose and regimen selection, optimal combinations, therapy duration, and study design for active development programsWork as part of a coordinated team under the oversight of a senior pharmacometrician within the PMx Oncology GroupThis is how you can make a differencePhD or Master's degree with extensive experience in Quantitative Systems Pharmacology or Systems Biology model development,Proven scientific track record and practical experience in several of the following areas: Statistical modelingModeling with differential equationsScripting languages (R, Matlab, Python)Drug developmentCritical thinking and self-reflectivePersistent and resilientAbility to connect unrelated concepts and generate original or unique ideasFluency in English required, German would be a plusAbout US Tech SolutionsUS Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.Internal Id:26-06120J-18808-Ljbffr