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In our state-of-the-art histology and immunohistochemistry laboratory, you'll support a variety of programs, ranging from discovery to clinical trials, all aimed at advancing antibody therapeutics.
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We are interested in the following topics: 1) B cell response in infection and vaccination at single-cell level; 2) Preventative and/or therapeutic monoclonal antibody development for different diseases; 3) HIV-1 fusion peptide vaccine development.
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Independently design, troubleshoot, and execute in vitro and ex vivo assays to narrow down promising hits from large antibody panels. Incubated in 82VS, Alloy Therapeutics' affiliated venture studio, Aakha Biologics was created through a collaborative partnership model that leverages access to Alloy's ATX-Gx transgenic mouse, suite of antibody discovery platforms, and discovery services.
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You will also maintain technical expertise in preclinical safety approaches applied to Immuno-Oncology therapeutics or Antibody Drug Candidates and awareness of industry trends. - Experience with the design and execution of in vivo studies to determine the effects of T Cell Engagers or Antibody Drug Conjugates on biological systems with line of sight to human safety may be considered an advantage.
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Familiarity with mass spectroscopy (MS) methods used for assessing mAb chemical stability and assessing ADC drug to antibody ratios including intact, reduced, and peptide mapping LC/MS. Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs.
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Perform Tissue Typing testing, including HLA typing by NGS, HLA flow crossmatch, solid phase HLA antibody testing, and cytotoxic HLA crossmatch, which are critical to solid organ and stem cell transplant programs.
Full-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases.
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The Antibody Solutions Division of Fortis Life Sciences is comprised of three wholly owned subsidiaries: Bethyl Laboratories, Abcore, and Arista Biologicals, Inc. The Quality Systems Manager position will be based primarily on site at Bethyl Laboratories located in Montgomery, TX which specializes in custom monoclonal and polyclonal antibody production services that support scientific discovery.
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Associate Principal Scientist - Antibody-Drug Conjugates Portfolio Team, Solids. As a key member of our antibody-drug conjugates (ADCs) portfolio team, you will lead a team focused on bringing new ADC projects into the portfolio and advancing them through all stages of pre-clinical development.
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Broad familiarity of difference disciplines within the life sciences ( e.g. PCR, recombinant DNA technology, protein expression and purification, chromatography, immunology, and antibody chemistry and binding kinetics.
$119,100 - $216,700 a yearFull-timeExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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The core platform technology comprises proprietary targeted lipid nanoparticles (tLNPs) that are composed of LNPs conjugated with a recombinant protein binder, such as a monoclonal antibody. Hands-on experience with various techniques such as qPCR, ddPCR, Sanger sequencing/NGS, ELISA, flow cytometry, and cell-based assays.
$130,000 - $145,000 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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The focus of the project will be to study the mechanisms of HLA class I and class II antibody-mediated graft injury leading to chronic antibody-mediated rejection (cAMR) with the aim of identifying potential therapeutic targets to prevent cAMR. These studies will include: Define a central role of TLR4 in mediating HLI and HLII-induced endothelial cell activation, pro-inflammatory signaling cascades, P-selectin externalization and monocyte recruitment.
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This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Graduate Degree in Instructional Design, Instructional Technology, Education, Applied Anthropology, Demography, Ethnography, User Experience Design or Research, Program Design or related field.
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Ideal candidate will have a significant background in plate-based assay development and antibody characterization including HPLC and Octet. BSc/MSc 3-6 + years in Molecular Biology, Chemistry, Analytical Chemistry, Organic Biochemistry considered, or equivalent combination of education and experience.
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As a scientist you will be responsible for the design and execution of in vitro display technologies for lead antibody identification/optimization and collaborating to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC. The candidate will leverage expertise to develop and implement research to gain a mechanistic understanding of the molecular pharmacology of therapeutic molecules.
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antibody job Title: post doctoral fellow Company: Emory University
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