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Planning and execution of mechanistic PKPD analyses to integrate knowledge of drug design parameters, disease pharmacology, physiology, pharmacokinetics and pharmacodynamics, and to optimize selection doses and preclinical study designs.
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Job Responsibilities:Perform preclinical pharmacology studies in rodents. Its service platform integrates preclinical studies with innovative animal models, CRISPR-based gene editing, and animal supplies, with the current focus on immuno-oncology and oncology.
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Strong knowledge of pharmacokinetics and pharmacodynamics principles, immunogenicity, modeling and simulation, ADME Concepts, and regulatory clinical pharmacology requirements. PhD, PharmD, or equivalent training in pharmacokinetics, pharmaceutical sciences, or related disciplines with at least 10 years of bio/pharmaceutical industry drug development experience in Clinical Pharmacology.
$150Full-timeExpandApply NowActive JobUpdated 2 months ago - UpvoteDownvoteShare Job
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Master Science or above in clinical pharmacology, pharmaceutical sciences or related areas such as pharmacokinetics. Lead cutting edge science, creativity, and novel approaches in clinical pharmacology and related areas.
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Collaborate with In Vivo Pharmacology and DMPK on the development of translational PK/PD models. VP of Clinical Pharmacology - Permanent - Fully remote from within US. PhD in Pharmacology, Pharmacokinetics, or related field.
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The selected candidate will join a newly created FNLCR laboratory at the NCI-Frederick campus that is within the NCI Molecular Pharmacology Branch (MPB), which employs state-of-the-art approaches to discover novel targets, evaluate investigational therapeutics, and develop novel drug combinations to improve treatment of recalcitrant, rare, and neglected cancers.
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Collaborate with In Vivo Pharmacology and DMPK on development of translational PKPD models. Develop and integrate timelines and budgets for clinical pharmacology activities with overall company timelines and goals, in close coordination with project management, clinical science, CMC, DMPK, nonclinical development, regulatory affairs and other stakeholders.
$262,000 - $321,000 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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The candidate will perform experiments and will provide technical support for studies executed within the In Vivo Pharmacology Group. The candidate will perform experiments and will provide technical support for studies executed within the In Vivo Pharmacology Group.
$41,250 - $60,500 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Strong knowledge of pharmacokinetics and pharmacodynamics principles, immunogenicity, modeling and simulation, Model-Informed Drug Development, ADME Concepts, and regulatory clinical pharmacology requirements to support clinical development and regulatory submission.
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Provide oversight for DMPK/clinical pharmacology related sample management activities including management of BA CROs. FogPharma has an exciting new opportunity for a Director, DMPK/Clinical Pharmacology reporting to our AVP, Clinical Pharmacology/Development DMPK. In this role, you will be responsible for the design and implementation of clinical pharmacology aspects of patient trials.
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At least 8 years' experience and a, PhD, PharmD or MD degree with emphasis in clinical pharmacology, pharmacokinetics or a related scientific discipline. As a Director within the Clinical Pharmacology Group at Gilead, you will have significant responsibility and accountability for clinical pharmacology programs in Virology.
$221,170 - $286,220 a yearFull-timeExpandApply NowActive JobUpdated 2 months ago - UpvoteDownvoteShare Job
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PhD, PharmD or equivalent in Pharmacokinetics, Pharmacology, Bioanalytical or related field with at least 5+ years of experience in Clinical Pharmacology, DMPK or related disciplines required.
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The modeler will collaborate closely with scientists across the non-clinical (in vivo pharmacology, bioanalysis, and toxicology) and clinical teams to provide feedback on interpretation of experimental data and on study design to advance the understanding of gene editing drugs.
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As a Scientist on the in vitro Pharmacology team, you will be an integral part of our research and development efforts, leading bioanalytical support functions and assay development. As a Scientist on the in vitro Pharmacology team, you will be an integral part of our research and development efforts, leading bioanalytical support functions and assay development.
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We use multi-disciplinary approaches ranging from behavioral neuroscience and in vivo electrophysiology to in vitro molecular and computational modeling and pharmacology. A postdoctoral fellow position is available at the laboratory of Yang Yang in the Department of Pharmacology of Pennsylvania State University, College of Medicine in Hershey, PA. We seek highly motivated and dedicated individuals to participate in our study on mechanisms of neural modulations in the brain affecting behavior.
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Title: pharmacology Company: Achaogen
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