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Collaborate with cross-functional teams, including Upstream Process Development, Analytical Development, and Manufacturing, to ensure seamless integration of processes. Startup is searching for a team-oriented Scientist II, Downstream Process Development (Viral Vector) to join company's Viral Vector team to support the process development of novel cell and gene therapies.
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Adverum’s core capabilities include clinical development, novel vector discovery and in-house manufacturing expertise, specifically in scalable process development, assay development, and current Good Manufacturing Practices quality control.
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The Sr. Research Associate will support the Discovery Bioscience team and assist in developing and executing screening assays for the evaluation of AAV vector products. Based on our innovative approach to developing genetic medicines, as well as our industry-leading internal manufacturing capability and expertise, we have become the Astellas Center of Excellence for their newly created Genetic Regulation Focus Area. We are currently exploring three gene therapy modalities: gene replacement, exon skipping gene therapy, and vectorized RNA knockdown, with plans to expand our focus and geographic reach under Astellas.
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The Quality Assurance (QA) Associate Director (AD) will be responsible for leading multiple shifts and two sites (Bothell and Seattle), who are involved in the daily activities of manufacturing, assessing and releasing drug products at the Bothell site, and providing quality oversight of Viral Vector Determination Team at Seattle (Dexter.
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We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products.
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Proficiency in Adobe Illustrator, Photoshop, InDesign, CorelDRAW, and other design software, with a strong understanding of vector and PNG file formats. Collaborate with web-based tools to manage a vast catalog of on-demand consumer products, ensuring manufacturing feasibility and product quality standards are met.
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Work closely with Embedded Software Engineers and Avionics to integrate vehicle sensor data such as GPS, IMU, Radar, and to control vehicle equipment such as valves, thrust vector controls, and landing grid fins.
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Applies various strategies, tools, and methods to write and generate RTL and structural code to integrate DFT.Optimizes logic to qualify the design to meet power, performance, area, timing, test coverage, DPM, and test time/vector memory reduction goals as well as design integrity for physical implementation.
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Prior experience in/knowledge of cell culture, viral vector manufacturing, recovery and/or purification of viral vector product in a manufacturing environment preferred. The Assistant/Associate Scientist/Engineer to join our Vector and Gene Delivery MS&T group in GDPAD. The successful candidate will design and execute experiments related to supporting commercial vector manufacturing processes.
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The incumbent in this role will support entry, junior, and experienced level professionals at the Libertyville Vector Manufacturing Facility (VMF), tasked with performing on demand, and. Minimum 7 years’ experience working directly with manufacturing and laboratory equipment (e.g., CTUs & CRTs, upstream and downstream equipment, Filler Machine, analytical lab equipment, autoclave, AKTA, etc.
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Products within the S&M subsystem that you will support include vehicle primary and secondary structures, landing and launch vehicle separation mechanisms, crew and cargo support mechanisms, and thrust vector control.
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Key Words: Analytical Development | Method Development | Assay Development | MDV | Protein Characterisation | Product Characterisation | Protein Analysis | AAV | Viral Vector | Gene Therapy | GMP | QC | Quality Control | CMC | Biologics | Biopharmaceutical | C> | ATMP.
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Our capabilities range from harness and cable assembly and electro-mechanical assembly to prototype manufacturing with a primary focus on integration and test – rack builds. Overview ELECTRICAL ENGINEER (PLTX)Bowhead seeks an Electrical Engineer to join our team in Plano, TX as part of the Manufacturing and Products Group.
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GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
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Work closely with Global Product Quality, External Manufacturing, and Supply Chain to understand forecasts and deadlines to ensure timely CoA/CoT (Certificate of Analysis/Certificate of Testing) generation for Cell Therapy vector products.
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