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The Director/Sr Director/Executive Director of Upstream Process Development will oversee the development of drug substance upstream processes for biologics within Lilly's biologics and emerging modalities portfolio.
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The Sr. Scientist of Upstream Process Development will oversee the development of all upstream technical activities (including microbial strain generation, fermentation/upstream process development) through the clinical development of recombinant norovirus vaccine program.
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As a member of the Upstream Process Development team, you will have the opportunity to learn to operate cutting-edge instruments and perform activities spanning the full cell line and cell culture production process.
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The Scientist, Upstream Tech Transfer (PD/Tech Transfer) will report to the Associate Director of Tech Transfer and will have responsibilities supporting the upstream process development.
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Work cross-functionally with Downstream Process Development, Analytical Development, Manufacturing, Regulatory, and Quality departments for upstream related process improvement, process validation, process change control, deviation investigation, and process characterization activities.
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Our client, a leading biotechnology company in Gaithersburg, MD, is seeking a dedicated Scientist to join their Upstream Process Development Department. As a Scientist II in the Upstream Process Development Department, you will be responsible for leading the design, optimization, and scale-up of upstream processes.
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Bachelor’s degree in a Scientific, Engineering or Biotech field with 4 years’ experience with upstream (fermentation/bioreactor) biologic production processes under GMP compliance. HS Diploma or Associate’s Degree with 5– 6 years’ experience with upstream (fermentation/bioreactor) biologic production processes under GMP compliance.
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Opportunity to work in an "ALL"stream environment that allows for cross-functional development between the differing manufacturing areas, i.e. media/buffer prep, upstream (US), downstream (DS), and fill finish (FF.
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The Upstream Process Development Scientist conducts upstream process optimization, purification of biomolecules, and further processing to establish end-to-end bio-manufacturing. Experience in the development and characterization of microbial fermentation and a good understanding of cell metabolism.
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AGC Biologics (AGC) is a global Contract Development Manufacturing Organization (CDMO) with bio-manufacturing facilities in Europe, Japan, Italy and the USA. The company provides a comprehensive range of commercial and clinical cGMP biologics manufacturing services, from DNA to active pharmaceutical ingredient (API.
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In this role you will participate in upstream and downstream areas of AAV development in the Pilot Plant for new gene therapy programs and processes. Display understanding of upstream and downstream process theory (i.e., Fermentation, Harvest, Tangential Flow Filtration, Column Chromatography) and equipment operation.
$26.38 an hourFull-timeExpandApply NowActive JobUpdated 8 days ago - UpvoteDownvoteShare Job
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Experience in upstream and downstream process development scale-up. The Research Associate I position will support process development by assisting in the development of methods for generation and purification of various bacteriophages.
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Subject Matter Expert in cGMP upstream manufacturing; especially with Mammalian Cell Culture, Roller Bottles, Rocker Bioreactors, Fed batch and Profusion Bioreactors, Cell Harvest Clarification, Viral Inactivation, Buffer and Media preparation, and equipment preparation.
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Experience in upstream process development is desirable. + Experience in upstream process development. Lead cell culture operations of a small team in the pilot-scale viral vector production lab to ensure supply of process intermediates to support Gene Therapy development activities.
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And with proteins expressed in mammalian cells with oversight of both upstream and downstream process development. Develop and optimize upstream and downstream processes to generate lead and Development Candidate TCR bispecific and to enable seamless technology transfer to contract manufacturing organizations.
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