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We are expanding our capabilities in informatics across multiple drug discovery platforms, including DNencoded library (DEL) screening, peptide-display discovery, support for RNbased therapeutics, parallel medicinal chemistry (PMC), targeted protein degradation, and high-throughput screening (HTS.
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The Therapeutics Discovery organization within Johnson & Johnson is continuing to build key scientific expertise in computational and medicinal chemistry, screening, and pharmacology to partner closely with our outstanding therapeutic area scientists to develop groundbreaking new medicines in the areas of Oncology, Immunology, Neuroscience, Cardiovascular, and Retina.
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Experience in preclinical malaria mouse challenge models, mosquito dissection, IVIS imaging, flow cytometry, fluorescence microscopy, antibody/protein purification, ELISA, ELISPOT. PhD in immunology, parasitology, cell biology, microbiology, biochemistry, or a related field.
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Must have extensive knowledge of protein chemistry, chromatography, and purification principles. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio.
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As a Senior Scientist, you will be at the center of our operations and you will be a member of our growing Cancer Immunology team and contribute to our efforts in target validation, identifying and evaluating novel therapies in the field of Cancer Immunotherapy.
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The Toxin Innovation Pharmacology Group at AbbVie is seeking a Principal Scientist who is highly motivated and innovative, and possesses strong leadership and communication skills to lead a neuromuscular junction in vivo research team.
$104Full-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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Proficient in LCMS peptide mapping for PTM analysis of antibodies, bispecifics, and similar protein therapeutics and mass spectrometry analysis of intact proteins. General understanding of CMC Analytical Development of protein therapeutics is desired.
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The lab scientist will be responsible for of the development of immuno-oncology assays. The role is ideal for individuals with skills in flow cytometry, protein technologies, molecular biology and display techniques.
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The Company is seeking to hire a Principal Scientist, Large molecule Pharmacokinetics expert to design and conduct PK/PD and biodistribution studies to support Discovery and Development of novel blood-brain-barrier penetrant transport vehicle (TV) biotherapeutics, including oligonucleotide transport vehicle conjugates.
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Identify and implement novel approaches within cross-functional areas including immunology, virology, antibody discovery, single cell approaches, and Next Generation Sequencing (NGS) to support innovative, rapid, and disruptive methods and technologies for antibody discovery.
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Minimum Requirements:BA or BS in Biology, Immunology, Cell Biology, Microbiology, Stem Cell Biology, Biotechnology or related scientific field5+ years experience working with imaging experiments – knowledge of how to set up and troubleshoot experiments (deep knowledge of sample preparation, acquisition and accurate controls)Proven experienced knowledge with imaging instruments – must know how to set-up, troubleshoot experiments.
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These include intellectual input and decision-making on protein targets to be pursued, development of immunogens and immunization strategies, utilization of hybridoma technology, and antibody validation in vitro and in vivo.
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Performs molecular biology experiments such as subcloning, genetic knockout or overexpression of target genes, ELISA, Western blotting, q-PCR, IP, CHiP assay, protein-protein or RNProtein interactions and drug screening; mouse handling such as tumor injection from clinical specimen, drug treatment and analyze all data as well as genetic mouse model handling.
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The Associate Scientist will be part of a team responsible for performing various analytical assays to support translational biomarker strategies for drug development candidates. 3+ years of experience in cell biology, molecular biology, immunology, pharmacology or a related field of biology.
$65,000 - $78,000Full-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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Scientist, Osteosarcoma Cell Therapy Initiative, UCSF Roybal Lab, Allen Lab SCHOOL OF MEDICINE – Microbiology and Immunology Description The mission of the UCSF Osteosarcoma Cell Therapy Initiative is to support the development of the next generation of cellular therapies to treat this disease.
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