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The successful candidate will have a strong background in bacterial expression and protein biochemistry, ideally hands-on experience with small molecule drug discovery. Experience with protein purification using an AKTA system and protein characterization using HPLC (analytical SEC), SDS-PAGE, and mass spectrometry.
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Principal Scientist, Protein Production and Process Development. Academic/PhD degree in Biochemistry, Biology, Bioengineering, Immunology, or related discipline. The incumbent will interface with internal preclinical Immunology, Protein Modality, and DECODE platform teams, as well as the internal CMC Leader, to provide protein reagents and protein leads, including data packages supporting Development Candidate nomination.
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The Protein Technologies Center (PTC) in the Department of Structural Biology is seeking a highly motivated Scientist with experience in protein and membrane protein biochemistry to join a newly funded GPCR collaborative project to investigate the molecular determinants and fidelity of GPCR signaling in health and disease.
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Candidates will have extensive experience (PhD holder or graduate with 4-5 years) in protein biochemistry, focusing on recombinant protein production, preferably in an industrial environment.
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Experience in protein biochemistry or structure biology. The Protein Engineering, Optimization and Design (PEOD) team within the Trait Discovery and Optimization (TDO) group combines protein engineering, structure biology, genomic analysis, and directed evolution to identify and improve novel insect control, herbicide tolerance, and agronomic traits.
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Prior experience in supporting protein X-ray crystallography, and biophysical characterizations of proteins is preferred, but not required. The candidate will be working in a highly dynamic group to provide protein purification support for a variety of small molecule drug discovery programs.
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The Goulding lab in the Department of Molecular Biology and Biochemistry at University of California, Irvine seeks to recruit an outstanding postdoctoral scientist with experience and interest in structural biology and biochemistry of protein complexes.
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Assisting with molecular biology and biochemistry techniques related to laboratory research projects such as PCR, molecular cloning, RNA/DNA isolation, and recombinant protein expression and purification.
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Requirements include technical proficiency in general laboratory practices with an emphasis on protein biochemistry and molecular biology experience. Primary lab functions include protein expression, protein purification on a high-throughput platform, and molecular cloning.
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We have the capabilities to analyze virtually any peptide, protein, or antibody, and have built a reputation for solving technical challenges related to assay development and validation. B.S. or M.S. in molecular biology, biochemistry, biophysics, immunology, or a related field with at least 1 year of experience.
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At least 2 years postgraduate, hands-on experience in mammalian cell culture and protein biochemistry such as SDS-PAGE, ELISA and affinity chromatography are required. The Research Associate will be responsible for conducting hands-on experiments including but not limited to molecular biology, mammalian cell culture, recombinant protein purification and characterization.
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Research Associate, Protein Science, protein expression, purification, microbial cell culturing, molecular cloning, biochemical synthesis, FPLC, SDS-PAGE, ELISA, colorimetric assays, Microsoft Office.
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PhD in Biochemistry or similar field with 5+ years of research experience in antibody discovery and/or protein engineering in an industry setting. Experience developing and working with various antibody discovery and protein engineering technologies such as mouse hybridoma, single B cell, phage/yeast/mammalian display, and/or computer-aided antibody/protein design is required.
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Develop & implement small-scale protein purification workflows by employing experience in protein purification techniques such as FPLC, IEX, SEC, HIC, etc. developing & implementing small-scale protein purification workflows by employing experience in protein purification techniques such as FPLC, IEX, SEC, HIC, etc.
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Develop and optimize state of the art antibody discovery and protein engineering technologies. Drive and manage antibody discovery and protein engineering activities to support various internal research projects.
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