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As a Pharmacokinetics Scientist, you will utilize your experience to further characterize the novel kinetics of our new therapeutic modality and build complex models that inform study designs and decision-making throughout the drug development process.
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You will apply model-based drug development concepts to impact decision making and expected to have experience and relevant training in pharmacokinetics. Experience in therapeutic areas of interest (neurology, immunology, immune-oncology, respiratory, pain.
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This includes all Biomarker Platforms' deliverables in clinical studies, for the supported assay measures (Pharmacokinetics, Immunogenicity including ADA and NAb, PD Biomarkers, Diagnostic Biomarkers, and Exploratory Biomarkers), from study start-up to regulatory submission.
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Acts as a consultant in the areas of pharmacokinetics and adverse reactions to physicians,nurses and other healthcare professionals. Reviews all laboratory data for appropriateness of medication use and recommends changes when needed, including microbial culture and sensitivity data, toxicology, therapeutic drug monitoring, etc.
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Founded in 2004, Pharmaron has invested in its people and facilities, and established a broad spectrum of research, development and manufacturing service capabilities throughout the entire drug discovery, preclinical and clinical development process across multiple therapeutic modalities, including small molecules, biologics and Cell & Gene Therapy products.
$120,000 - $150,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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As part of the Clinical Pharmacology, Modeling and Simulation department, the Modeling and Simulation Senior Scientist will support Amgen clinical development and translational sciences programs across multiple therapeutic areas.
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The qualified candidate will apply knowledge and technical expertise to characterize systems biology, pharmacokinetics, and pharmacodynamics-related aspects facilitating research efforts across a diverse portfolio of diseases and therapeutic approaches.
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Frontage Laboratories Inc. is an award winning, publicly listed (HKSE), full-service CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China, and growing over 30% YOY. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
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PhD, PharmD or MD with 3+ years experience in clinical pharmacology, pharmacokinetics, pharmaceutics, pharmacometrics, (bio)statistics, biomedical engineering, or a related discipline. Serve as a project team representative, support project teams across multiple therapeutic areas, provide input on clinical pharmacology and biomarker studies and contribute to project teams.
$210,000 - $250,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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PKDM works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to design promising clinical therapeutic candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.
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Experimental platforms to evaluate pharmacodynamics, safety pharmacology, and pharmacokinetics of our therapeutic leads. studies to evaluate PK/PD and safety of AAV-based therapeutic leads in oncology.
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Supervise all phases of bioassays to support pre-clinical and clinical pharmacokinetics, PD Biomarkers; We leverage local regulatory and therapeutic expertise across all major areas including oncology, cardiology, metabolic disease, endocrinology, central nervous system, anti-viral and anti-infective.
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PhD, PharmD or equivalent in Pharmacokinetics, Pharmacology, Bioanalytical or related field with at least 5+ years of experience in Clinical Pharmacology, DMPK or related disciplines required. Knowledge of pharmacokinetics and pharmacodynamics (PK/PD) and DMPK principles.
$150,000 - $190,000 a yearFull-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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Antibody diversity (e.g.sequencing and analysis of immune repertoires), and/or pharmacokinetics/pharmacodynamics. Advancing BigHat therapeutic programs through ownership of the entire data science life cycle from experimental design through data analysis and modeling, including implementation of novel antibody design strategies, development of robust data pipelines for assays of antibody function and developability, and data-driven improvements to our statistical and ML models.
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Implements, optimizes and performs immunochemical, biochemical and cellular assays to characterize binding, potency, pharmacokinetics and mechanism of action of antibody candidates. Supports therapeutic antibody discovery projects related to Cancer-Immunology, Oncology as well as Ocular diseases.
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