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15 years relevant work experience in clinical pharmacology and project management in a function as Clinical Pharmacologist, Scientist, Research Physician or a comparable function in clinical research.
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Proficient understanding and application of cytochrome enzyme inhibition, induction, drug transporter functionality, and their effects on pharmacokinetics (PK) and drug-drug interactions (DDI) Lead the formulation and execution of comprehensive DMPK and pharmacokinetics-pharmacodynamics (PKPD) strategies to steer lead optimization and developmental projects, ensuring alignment with project objectives, milestones, and progression of development candidates.
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Minimum 8+ years of research experience in an industry setting experience in design, execution, and analysis of murine models of cancer, inflammation, pharmacokinetics/pharmacodynamics (PK/PD), toxicology and/or immunology.
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Experimental platforms to evaluate pharmacodynamics, safety pharmacology, and pharmacokinetics of our therapeutic leads. Senior Discovery Scientist, Pharmacology (Genetic Medicines) Our headquarters are in South San Francisco, and we are building a world-class team to translate two decades of progress in DNA computing and synthetic biology into the clinic.
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MS or PhD in organic chemistry, analytical chemistry, Drug Metabolism and Pharmacokinetics or related science such as Pharmacology, Biology, Biochemistry. We are seeking an exceptional individual for a Principal Scientist position within the DMPK group.
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Test transferred methods or develop bio-analytical methods for the assessment of pharmacokinetics, pharmacodynamics, and immunogenicity of bio-pharmaceutical compounds in biological matrices by use of ligand binding based assay applied to a variety of technology platforms including but not limited to ELISA, Gyros, Simoa, Luminex, Mesoscale Discovery, and Flowcytometry, Real-time PCR, ddPCR, and NGS in a manner consistent with current regulatory expectations for bioanalysis.
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SimBioSys ( is seeking an exceptionally talented computational scientist to work on one of the most important challenges in medicine - delivering on the promise of precision medicine. Areas of interest should include pharmacokinetics/pharmacodynamics, biochemical kinetics, and cancer-immune cell interactions.
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Pharmacology & Biomarker Discovery team of the Institute of Medicine (IOM) at Altos Labs. We are seeking a highly skilled, self-motivated and talented scientist to lead and execute. Pharmacology, Science Integration, Innovation and Insights, Drug Metabolism and Pharmacokinetics, etc.
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Frontage Laboratories Inc. is an award winning, publicly listed (HKSE), full-service CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada, and China, and growing over 30% YOY. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
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Senior Principal Scientist, Pharmacokinetics & Drug Metabolism. The Senior Principal Scientist will be responsible for supporting small molecule drug discovery through to clinical development with the opportunity to expand support to other therapeutic modalities, such as antibody drug conjugates, targeted protein degraders, etc.
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Senior Data Scientist, Computational Biology Department: DS/ML (Data Science/Machine Learning) , antibody diversity (e.g.sequencing and analysis of immune repertoires), and/or pharmacokinetics/pharmacodynamics.
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DPI has both technology development components and collaborative resource access programs, covering small molecule and RNAi screening technologies and informatics, and catalyzes translational efforts in biology, medicinal chemistry, pharmacokinetics, toxicology, absorption, distribution, metabolism, excretion (ADME), and project management.
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Apply expertise in drug metabolism and pharmacokinetics (DMPK) principles and translational QP and PKPD methodologies as studies move from preclinical to clinical phases. In this role the qualified candidate will act as a lead preclinical PKPD modeling expert in interdisciplinary teams to support the drug discovery and development process by applying his/her knowledge and technical expertise to quantitatively characterize the pharmacokinetics, pharmacodynamics, and biomarker (PK/PD/Biomarker) properties of drug candidates.
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Amgen is seeking a highly motivated scientist to join the Pharmacokinetics & Drug Metabolism (PKDM) department at our site in South San Francisco, California. The Bio-transformation Principlal Scientist leader will be in charge of implementing cutting edge separations and mass spectrometry tools (LC/MS) for the identification, quantitative and qualitative analysis of novel drug candidates and their metabolites from in vitro and in vivo biological matrices.
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As a Discovery DMPK Biopharm bioanalyst, you will be part of a team responsible for the analysis of Biopharm molecules using state of the art equipment to understand Pharmacokinetics/Toxicokinetics, target engagement and anti-drug antibodies in a fast-paced discovery laboratory environment, allowing you an opportunity to utilize, challenge, and expand your bioanalytical skill set.
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