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Develop and drive the DMPK, TK and pharmacokinetics-pharmacodynamics (PKPD) strategy for development projects to support project decisions, milestones and development candidate advancement.
$129,500 - $191,500 a yearFull-timeExpandApply NowActive JobUpdated 10 days ago - UpvoteDownvoteShare Job
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PhD in pharmacokinetics, chemistry, biochemistry, or a related scientific discipline. Collaborate with Business Development and scientific leadership of DMPK to identify, pursue, and close new opportunities.
ExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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PhD, PharmD or equivalent in Pharmacokinetics, Pharmacology, Bioanalytical or related field with at least 5+ years of experience in Clinical Pharmacology, DMPK or related disciplines required.
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PhD or PharmD degree or equivalent degree with specialization in pharmacology or pharmacokinetics, or in a related scientific discipline. Interpret DMPK data with a focus on translation and applies information to support clinical pharmacology study design and strategy.
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Responsibilities:We are currently seeking a Director, Drug Metabolism and Pharmacokinetics, who will have scientific oversight of one or more of the small molecule discovery projects and will manage the in vitro and in vivo PK, ADME and bioanalytical assays.
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The GlaxoSmithKline U.S. Drug Metabolism and Pharmacokinetics (DMPK) organization is responsible for the delivery of key DMPK support (in vitro, pharmacokinetic/toxicokinetic, and bioanalytical) that helps drive early drug discovery programs.
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General background and understanding of in vitro and in vivo pharmacology, quantitative structure-activity relationships, physics-based modeling, and simulation, and drug metabolism and pharmacokinetics pertaining to CNS drug development are desirable.
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PhD in Pharmacometrics, Pharmacokinetics/Pharmacodynamics, Clinical Pharmacology, DMPK, Pharmaceutics, Computational Sciences, Engineering, or a related field. Thorough understanding of pharmacokinetics and/or pharmacodynamic principles along with an ability to clearly communicate theories and concepts.
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Collaborate closely with cross-functional teams, including clinical development, non-clinical development, DMPK, regulatory affairs, and clinical operations, to ensure alignment and integration of clinical pharmacology principles throughout the drug development process.
ExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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PhD and PostDoc in Pharmacokinetics, Chemistry, Drug Metabolism, Pharmaceutical Sciences, or related fields, with a minimum of 10 years of industry experience. Act as the subject matter expert in DMPK, representing the department in project team meetings and contributing to strategy development.
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The QTAS group supports Discovery and Development Projects by generating in vitro ADME data, pharmacokinetics characterization, prediction of human efficacious dose/pk and drug-drug interactions (DDI) and in vitro to in vivo extrapolations for clinical candidates.
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Solid working knowledge of Pharmacokinetics, PK/PD principles applied to modeling, ADME and clinical pharmacology concept and understanding of regulatory guidelines on DMPK/ clinical pharmacology studies to support early oncology drug development.
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We are currently seeking a Director, Drug Metabolism and Pharmacokinetics, who will have scientific oversight of one or more of the small molecule discovery projects and will manage the in vitro and in vivo PK, ADME and bioanalytical assays.
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A biotechnology company is seeking a DMPK expert to support its long-acting antibodies and precision immunology approaches for inflammatory diseases. Ph. D. in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, or related science discipline.
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The focus of the role is new business development for pre-clinical / non-clinical toxicology and drug safety services in pharmaceutical drug development, and services including DMPK and related bioanalytical.
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