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Serve as DMPK and BA representative on project teams supporting the development of novel drug candidates (small molecules, possibly biologics and antibody drug conjugates) for the treatment of diseases in Oncology, and Immuno-Oncology.
$129,500 - $191,500 a yearFull-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy, and Epigenetics) to help address unmet clinical needs in a host of cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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You'll have experience in cell and immuno-oncology based assays, including flow cytometric and plate-based methods for preclinical drug discovery & functional validation. You will have (extensive) knowledge and practical experience in immuno-oncology/ T-cell biology from an industrial drug discovery background, encompassing from early stage discovery to pre-clinical validations.
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They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments.
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Extensive knowledge and understanding of other areas of cancer cell biology including but not limited to DNA damage and repair, immuno-oncology, oncogenic signaling, ADC biology and/or apoptosis.
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We are seeking an energetic and motivated Scientist with deep scientific and technical expertise in immunology or immune-oncology with a track record of scientific excellence to join our team in Cambridge, MA USA. As a Scientist in Breakthrough Lab you will be a key member of a team focused on supporting immunology and immuno-oncology projects through the drug discovery and development process.
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Performs gating, analyses and scientific review of high dimensional flow cytometry data collected from immuno-oncology clinical trials. Troubleshoot and analyze complex data in support of drug discovery projects.
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Our programs span discovery-stage to late-stage development and cover a range of high-value indications in rare diseases and immuno-oncology. Centessa places a premium on learnings from its clinical trials, whereby a drug has established the relevance of a biological pathway contributing to disease outcome.
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Additionally, the laboratory now has a major focus in the field of immuno-oncology, evaluating multiple innovative cell-based immune therapy approaches in targeting ovarian cancers. Project Scientist - UCLA G.O. Discovery Laboratory University of California Los Angeles Requisition Number: JPF09292 The G.O. Discovery Laboratory within the UCLA Eli and Edythe Broad Cell Research Center, which is closely affiliated with the Jonsson Comprehensive Cancer Center and the Molecular Biology Institute, invites applications for a Project Scientist at the Assistant, Associate or Full Project Scientist level.
ExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Additionally, 10+ years’ experience participating effectively on cross-disciplinary teams in pharmaceutical or biotech industry, including a minimum of 2-3 years in oncology clinical drug development is required.
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Demonstrated scientific acumen and mechanistic understanding of disease biology and experience in oncology and immuno-oncology drug development (small molecule and biologics) is highly desirable.
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The Vice President of Business Development will engage with pharmaceutical companies and hospitals to commercialize Pear Bio’s precision medicine platform and drug discovery pipeline. Our patient data, biobank and biomarker technology have led to the creation of an in-house drug discovery pipeline for cancers with high unmet need.
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
ExpandApply NowActive JobUpdated 14 days ago - UpvoteDownvoteShare Job
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Broad understanding of oncology disease area; experience in immuno-oncology highly desirable. The ideal candidate is an MD or MD/PhD scientist with a clinical perspective, coupled with a track record of exceptional achievement in oncology therapy development.
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Preference for candidates with a strong track record in cancer drug discovery/translational research and the targeting of epigenetic pathways by small-molecule inhibitors. Pfizer's Oncology Research Unit (ORU) unit in La Jolla, California, is seeking a Principal Scientist (PhD) to join the Post-CAN Research group focused on translating basic discoveries in the field of cancer cell biology into novel therapeutics.
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