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In our state-of-the-art histology and immunohistochemistry laboratory, you'll support a variety of programs, ranging from discovery to clinical trials, all aimed at advancing antibody therapeutics.
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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You will also maintain technical expertise in preclinical safety approaches applied to Immuno-Oncology therapeutics or Antibody Drug Candidates and awareness of industry trends. - Experience with in vitro cellular biology/immunology assays applied to physiologically relevant human cellular models, flow cytometry, multiplex cytokine measurements, activation and cytotoxicity assays, micro-physiological systems, 3D organoids, membrane protein arrays, omics technologies, confocal imaging.
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Broad familiarity of difference disciplines within the life sciences ( e.g. PCR, recombinant DNA technology, protein expression and purification, chromatography, immunology, and antibody chemistry and binding kinetics.
$119,100 - $216,700 a yearFull-timeExpandApply NowActive JobUpdated 7 days ago - UpvoteDownvoteShare Job
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Experience or familiarity with immunology, cancer biology, and/or antigen/antibody production/purification is a plus. Aethon is funded by Apple Tree Partners (ATP), a leader in life sciences venture capital, with $2.65 billion in committed capital.
$80,000 - $95,000 a yearFull-timeExpandApply NowActive JobUpdated 9 days ago - UpvoteDownvoteShare Job
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Postdoctoral Position in Immunology at UCLA University of California Los Angeles Requisition Number: JPF09114 The laboratories of Dr. Elaine F. Reed (Department of Pathology and Laboratory Medicine.
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We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio.
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As a scientist you will be responsible for the design and execution of in vitro display technologies for lead antibody identification/optimization and collaborating to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC. The candidate will leverage expertise to develop and implement research to gain a mechanistic understanding of the molecular pharmacology of therapeutic molecules.
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Background in immunology and immuno-oncology are desired. Your day-to-day will involve:Engaging in dynamic discussion laboratory personnel in our US and European locations to guide them in developing IHC/IF single-plex/multi-plex assays and in situ hybridization (ISH)Partnering closely with our digital pathology team and data scientists to develop and verify digital image analysis algorithms and results from image analysis projects.
$170,625 - $284,375 a yearFull-timeExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Experience in pooled or arrayed high throughput screening pipelines, immunology, immunotherapy, antibody discovery/development, gene engineering, genomics, computational biology, or synthetic biology preferred.
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Utilizes professional knowledge of: theories, principles, methods, and techniques of immunology, cell biology, and microbial pathogenesis, such as ELISA, ASC assays, cellular proliferation assays, western blotting, cell culture, small animal handling (such as mice or guinea pigs), and aseptic technique.
Full-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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You will have hands-on experience in ligand binding/antibody assay development and will be interested in projects requiring close collaboration with other groups, such as discovery research, product sciences, process development, and QC.
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Our preclinical pipeline extends beyond to biologics against novel immuno-oncology targets, antibody-drug conjugates, bispecific and trispecific antibodies, and small molecules expected to reach the clinic in 6-24 months, underscoring our bench-to-bedside approach.
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As core member of multi-disciplinary drug discovery teams, you will direct investigative toxicology strategies to predict, assess and mitigate target- and modality-related safety risks in discovery programs, with a focus on Antibody-Drug Conjugates.
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We are interested in the following topics: 1) B cell response in infection and vaccination at single-cell level; 2) Preventative and/or therapeutic monoclonal antibody development for different diseases; 3) HIV-1 fusion peptide vaccine development.
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