Upvote
Downvote
Sr. Research Associate, Potency Assays
Share Job
- Suggest Revision
$104,000 - $125,000 a year
Full-time
- We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products.
- We have built a deep portfolio of AVV-based gene therapy product candidates, with five product candidates in clinical trials: 4D-150 for the treatment of wet age-related macular degeneration (wet AMD) and diabetic macular edema (DME), 4D-710 for the treatment of cystic fibrosis lung disease, 4D-310 for the treatment of Fabry disease cardiomyopathy, 4D-125 for the treatment of X-linked retinitis pigmentosa (XLRP), and 4D-110 for the treatment of choroideremia.
- Opportunities to expand to other indications and modalities within genetic medicine Senior Research Associate will primarily focus on executing routine cell-based testing as per approved SOPs (QC-focused) for lot release/stability, comparability and formulation assessment of drug substances and drug products in accordance with cGMP standards, and contribute to develop, optimize and validate new cell-based assays, drafting SOPs and data analysis.
- Develop, optimize, and execute bioassays including cell-based, nucleic acid-based, ELISA, and enzymatic assays with a strong scientific understanding of the analytical procedures and applicability of the emerging or existing assay platforms.
- Understand phase-appropriate GMP requirements for AAV-based gene therapy products.
Active Job
Updated TodaySimilar Job
Relevance
Active