Slingshot Biosciences

We currently have a suite of products that allow for rapid, stable instrument deployment and are poised to make headway into clinical markets with controls for engineered cell therapies.. Slingshot Biosciences is seeking an experienced Process Development Scientist to support the scaling and transfer of our synthetic cell product lines from R&D into Manufacturing in a design control environment.. Design, execute, optimize and validate biochemical conjugation processes, reagent formulations, flow cytometry based assays, QC test methods, verification and validation studies, and stability studies.. PhD in bioengineering, molecular biology, biochemistry, or related field with 5+ years industry experience, or Masters with 8+ years industry experience, or Bachelors with 10+ years experience.. Experience in several of the following is required (the more the better): Flow cytometry experience Protein and conjugation chemistry experience Design control/Technology transfer/MSAT/Process Transfer/Process development experience.

process development

Our north star is to make healthcare more accessible around the world. We are doing this by advancing cell biology to develop innovative solutions for human health. Founded in 2012, and located in one of the largest biotech hubs in the world, Slingshot Biosciences is a growing life sciences company with a platform technology and paradigm-shifting mission to make synthetic cells the gold standard for all cell-based applications. We currently have a suite of products that allow for rapid, stable instrument deployment and are poised to make headway into clinical markets with controls for engineered cell therapies. At Slingshot, we value diversity and believe that a variety of backgrounds and experiences leads to more innovative ideas and a better understanding of our customers. Passion is at the core of our values, and employees are encouraged to pursue their passions in their work and contribute to the company's overall mission. We desire motivated team members who appreciate the freedom to be creative and think outside the box to solve problems. We offer an environment where employees are empowered to take ownership of their work, and have the ability to quickly contribute new ideas and iterate on current processes. In everything we do, we are dedicated to delivering top-quality products and services to our customers which ultimately makes a significant impact on patient care. Slingshot Biosciences is a growing life sciences company with a platform technology and paradigm-shifting mission to make synthetic cells the gold standard for all cell-based applications. We currently have a suite of products that allow for rapid, stable instrument deployment and are poised to make headway into clinical markets with controls for engineered cell therapies. At Slingshot, we value diversity and believe that a variety of backgrounds and experiences leads to more innovative ideas and a better understanding of our customers. Passion is at the core of our values, and employees are encouraged to pursue their passions in their work and contribute to the company's overall mission. We desire motivated team members who appreciate the freedom to be creative and think outside the box to solve problems. We offer an environment where employees are empowered to take ownership of their work and to contribute new ideas. In everything we do, we are dedicated to delivering top-quality products to positively impact patient care. Slingshot Biosciences is seeking an experienced Process Development Scientist to support the scaling and transfer of our synthetic cell product lines from R&D into Manufacturing in a design control environment. Proactive communication, diligent execution and documentation of complex workflows, and a highly collaborative mindset are critical to success in this role. We also place a premium on creativity, intellectual curiosity, flexibility, resiliency, drive, and a proactive, can-do attitude. This is a full-time, on-site position at Slingshot's headquarters in Emeryville, CA, reporting to the Senior Manager of Process Development. For the successful candidate this will be a fantastic opportunity in a dynamic, fast-paced environment and a chance to deliver products that will positively impact human health. Responsibilities <ul> <li>Transform small-scale R&D synthesis workflows (e.g., conjugation of biomarkers to synthetic cells) into validated, sustainable, production-scale manufacturing workflows in close collaboration with R&D scientists, systems engineers, and manufacturing technicians.</li> <li>Design, execute, optimize and validate biochemical conjugation processes, reagent formulations, flow cytometry based assays, QC test methods, verification and validation studies, and stability studies.</li> <li>Identify critical raw materials as well as alternatives, validate alternate suppliers. </li> <li>Ensure that product vision is maintained and realized through execution and documentation of design control processes, and conduct technical and design reviews.</li> <li>Create manufacturing procedures and documentation, BOMs, routings, costing, etc. for transfer to internal and external teams.</li> <li>Support and/or coach R&D/manufacturing staff in similar scale-up and transfer efforts as needed.</li> <li>Monitor production workflows after hand-off, continually identifying areas for process improvement, risk mitigation, optimization, and automation.</li> <li>Perform other duties as assigned.</li> </ul>Requirements<ul> <li>PhD in bioengineering, molecular biology, biochemistry, or related field with 5+ years industry experience, or Masters with 8+ years industry experience, or Bachelors with 10+ years experience.</li> <li>Experience in several of the following is required (the more the better): <ol> <li>Flow cytometry experience</li> <li>Protein and conjugation chemistry experience</li> <li>Design control/Technology transfer/MSAT/Process Transfer/Process development experience.</li> </ol> </li> <li>Experience with the following is preferred: lab automation (especially automated liquid handling, e.g. Hamilton or similar), stability studies, immunoassays, polymer chemistry, protein expression systems, statistical methods, design control including V&V / Gage R&R, project management, quality management system, GMP, ISO-13485.</li> <li>Excellent communication, presentation, interpersonal, and organizational skills, meticulous attention to detail.</li> <li>Proactive approach to time management and effective task prioritization.</li> <li>Strong problem-solving skills, eagerness and ability to troubleshoot experimental issues independently.</li> </ul>Our salary ranges are calculated by role and level. Your position within that range will be determined by your job-related knowledge, skills, experience, relevant education, and training/certifications. In addition to those factors, we also examine internal equity as well as consider current market rate, and title may be assessed one level lower or higher accordingly. After you join the company your performance, contributions, and results along with business and organizational needs will affect your base salary. The base salary range for this full-time position is between $120,000 - $150,000 + equity + benefits. What we offer at Slingshot:<ul> <li>Health Care Plan (Medical, Dental & Vision)</li> <li>Retirement Plan (401k)</li> <li>Stock Option Plan</li> <li>Paid Time Off (Vacation & Sick)</li> <li>Family Leave</li> <li>Life Insurance</li> <li>Fully stocked break room with food, snacks and beverages</li> </ul> Slingshot Biosciences requires employees to be vaccinated against COVID-19 unless they have an approved medical or religious accommodation. Proof of such vaccination will be required as part of the hiring process. Slingshot Biosciences is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law. Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.

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