Merck

Located in the greater New York City metropolitan area, research conducted in our state-of-the-art facility drives all aspects of drug discovery, development, manufacture, and commercialization of small molecules, biologics, and vaccines.. The successful candidate will join collaborative, multidisciplinary discovery teams across our company’s sites to invent novel medicines by merging the frontiers of data science and machine learning with medicinal chemistry, HTE and automation.. Interacting with medicinal chemistry project teams, modeling and chemo-informatics experts, pharmacologists, and analytical chemists to design the highest quality chemistry approaches to macrocyclic peptides, target protein degraders and small molecules that will advance our company’s drug discovery programs.. Creatively using deep knowledge of synthesis, chemo-informatics, and cutting-edge high-throughput experimentation techniques to rapidly solve medicinal chemistry problems of the highest complexity.. Utilizing strategic thinking skills to help shape the vision of Rahway Discovery Chemistry to create a new paradigm for success in medicinal chemistry.

senior scientist

Job Description Our research laboratories in Rahway, New Jersey are focused on the discovery and development of world-changing therapeutics. Co-located with the corporate headquarters, our multi-disciplinary research site offers cutting edge technology and resources to explore the most promising science combined with our company’s world-class R&D expertise for inventing medicines. Located in the greater New York City metropolitan area, research conducted in our state-of-the-art facility drives all aspects of drug discovery, development, manufacture, and commercialization of small molecules, biologics, and vaccines. At our company, we are inspired by the belief that a research-driven enterprise dedicated to scientific excellence can create medicines and vaccines that save and improve lives. Every employee is building on our proud legacy of scientific breakthrough to impact the lives of patients, which relies on the integrity, creativity, humility, and scientific acumen of our team. We are creating a diverse organization that is inspired by invention and founded on a culture of respect and collaboration. At our research laboratories, you will have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career. Job Description: Our Company is currently seeking exceptional chemists for a Senior Scientist position within the High-Throughput Experimentation (HTE) group in the New Jersey Discovery Chemistry Department located in Rahway, New Jersey. The successful candidate will join a highly collaborative cross-functional team of scientists whose mission is to fundamentally change the way new medicines are invented. Leveraging our company’s world-leading Center for High-Throughput Experimentation, the successful candidate will apply their knowledge and experience in synthetic chemistry to discover and develop innovative, high value synthetic methods to advance discovery chemistry programs across all modalities including macrocyclic peptides, target protein degraders and small molecules. The successful candidate will join collaborative, multidisciplinary discovery teams across our company’s sites to invent novel medicines by merging the frontiers of data science and machine learning with medicinal chemistry, HTE and automation. A mindset of Innovation and continual technological improvement is an important aspect of this role. Success across this spectrum of activities will require the application of the latest advances in chemistry to develop innovative approaches for addressing new chemistry challenges across multiple modalities. The successful candidate must have excellent interpersonal, collaboration and communication skills in a team environment. Responsibilities Include But Are Not Limited To: <ul><li>Interacting with medicinal chemistry project teams, modeling and chemo-informatics experts, pharmacologists, and analytical chemists to design the highest quality chemistry approaches to macrocyclic peptides, target protein degraders and small molecules that will advance our company’s drug discovery programs.</li><li>Creatively using deep knowledge of synthesis, chemo-informatics, and cutting-edge high-throughput experimentation techniques to rapidly solve medicinal chemistry problems of the highest complexity.</li><li>Innovating on the critical path to invent new synthetic methods to solve key program issues where existing methods are insufficient.</li><li>Apply data science techniques, including the use of machine learning and predictive modeling, to analyze large-scale experimental data and extract insights to drive iterative designs.</li><li>Building and keeping a strong presence the external chemistry community through high impact publications, external presentations and external collaborations.</li><li>Utilizing strategic thinking skills to help shape the vision of Rahway Discovery Chemistry to create a new paradigm for success in medicinal chemistry. </li></ul>Education Minimum Requirement: <ul><li>PhD in Synthetic Organic or Organometallic Chemistry OR expected attainment of PhD in 2024 matching noted criteria. </li></ul>Required Experience And Skills: <ul><li>Expertise in synthesis and modern catalytic methods</li><li>Proven ability to devise innovative solutions to challenging problems in synthesis and catalysis.</li><li>Must have excellent interpersonal, collaboration, and communication skills and a proven record of solving complex problems in a team environment. </li></ul>Preferred Experience And Skills: <ul><li>Strong history of publication in peer-reviewed journals</li><li>Experience in computer programming and/or data science </li></ul>NOTICE FOR INTERNAL APPLICANTS In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions. If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor. Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission. Current Employees apply HERE Current Contingent Workers apply HERE Secondary Language(s) Job Description US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. We Are An Equal Opportunity Employer, Committed To Fostering An Inclusive And Diverse Workplace. All Qualified Applicants Will Receive Consideration For Employment Without Regard To Race, Color, Age, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Protected Veteran Status, Or Disability Status, Or Other Applicable Legally Protected Characteristics. For More Information About Personal Rights Under The U.S. Equal Opportunity Employment Laws, Visit: EEOC Know Your Rights EEOC GINA Supplement Pay Transparency Nondiscrimination We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts U.S. Hybrid Work Model Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”. Under New York State, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education. Expected Salary Range: $111,400.00 - $175,300.00 Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here. Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic VISA Sponsorship: Yes Travel Requirements: 10% Flexible Work Arrangements: Not Applicable Shift: 1st - Day Valid Driving License: No Hazardous Material(s): N/A Job Posting End Date:05/14/2024 A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Requisition ID:R293358

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