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Senior Scientist - Developability
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Full-time
- Senior Scientist Biotherapeutics DevelopabilityBristol Myers Squibb is seeking a highly motivated and innovative Senior Scientist with demonstrated expertise in antibody developability and characterization of monoclonal antibodies, bi/multispecifics, Fc-fusion proteins, and antibody-drug conjugates (ADCs) to join our Discovery Biotherapeutics team.
- This role will work in close collaboration with the protein engineering and characterization teams to test, design and optimize early to late-stage therapeutics to accelerate biotherapeutic discovery.
- The ideal candidate should also have knowledge/experience in protein chemistry, protein engineering, modeling and prediction, and generation of large high-quality datasets to aid in generating training datasets for AI/ML guided therapeutic design.
- Proactively identify liabilities for antibody developability, manufacturability or pharmacokinetics and work with protein engineering teams to guide design and optimization using sequence and computational prediction tools.
- Experience in antibody conformational/thermal stability (e.g., Tm/Tagg, DSF, DSC, etc
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