EMPIRICO

Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a talented chemist with experience in solid-phase oligonucleotide synthesis and analytics.. Perform solid phase synthesis, purification, and characterization of oligonucleotides and oligonucleotide conjugates. This position requires a PhD in Organic Chemistry, or a Master’s degree in combination with at least one year of experience in a GMP lab environment. Experience with RPIP-HPLC, AEX-HPLC, UV, NMR, LCMS, MALDI, and HRMS is highly desired. Analytical or purification method development experience using RPIP-HPLC and AEX-HPLC

senior scientist

Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a talented chemist with experience in solid-phase oligonucleotide synthesis and analytics. This is an excellent opportunity for a highly-motivated, creative scientist to be a vital member of our team.
Responsibilities: Perform solid phase synthesis, purification, and characterization of oligonucleotides and oligonucleotide conjugates
Analyze, interpret, and communicate synthetic and analytical results
Present results at group meetings to senior staff
Troubleshoot and optimize current procedures
Ability to multitask and work on several projects simultaneously
Requirements: This position requires a PhD in Organic Chemistry, or a Master’s degree in combination with at least one year of experience in a GMP lab environment
Experience with High-Performance Liquid Chromatography
Desire to work in a fast-paced and dynamic environment
1-7 years of relevant work experience, preferably in solid phase synthesis
Experience with RPIP-HPLC, AEX-HPLC, UV, NMR, LCMS, MALDI, and HRMS is highly desired
Analytical or purification method development experience using RPIP-HPLC and AEX-HPLC
Applicants must have authorization to work in the U.S.
The estimated base salary range for this role is $75,000 to $140,000. Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. We offer a wide range of benefits including a retirement savings plan (with company match), paid vacation, holidays, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.
About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform for genetically-validated target discovery and the siRCH platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.
We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place. #J-18808-Ljbffr

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