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Scientist I, Preclinical Bioanalytical
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- The core platform technology comprises proprietary targeted lipid nanoparticles (tLNPs) that are composed of LNPs conjugated with a recombinant protein binder, such as a monoclonal antibody.
- The Scientist I, Preclinical Bioanalytical will play a key role in the pre-clinical team developing and applying a broad range of assays to support product testing in a broad range of preclinical models.
- By developing a suite of species-specific bioanalytical assays such as immunogenicity/ADA, biomarker, pharmacokinetic and dynamic assays spanning a range of technology platforms (ELISA, ECL, PCR, LC-MS) as well as being fluent in the analysis of flow cytometry data, the candidate will support a wide range of in vitro and in vivo studies and their endpoints, all critical to supporting product development.
- Bioanalytical Assays including pharmacokinetic and pharmacodynamic as well as biomarker and immunogenicity assay development and participation in translation of these preclinical assays to clinic.
- Process and analyze ex vivo or in vitro samples through flow cytometry, molecular biology and other analytical techniques including ELISA and other Ligand binding assays.
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