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- Synthesis, optimization, and high-quality delivery of various polymer, protein/peptide, and lipidated bioconjugates in support of discovery and development of novel therapeutics, with an emphasis on oligonucleotides
- Development and implementation of new linker chemistries/spacers and bioconjugation methods for targeted drug delivery
- Collaboration with internal and external partners for material transfer to support in vitro and in vivo POC experiments; assemble data packages and maintain quality control documentation through Benchling for final product delivery.
- In-depth experience in bioconjugate purification techniques including various liquid chromatography methods (e.g. RP, IEX, SEC, HIC, affinity, FPLC) and membrane filtrations (e.g. TFF)
- Prior experience in biochemistry techniques and analytical methods such as SEC-MALs, LCMS, SPR/BLI, ELISA, SDS-PAGE, enzyme activity assays, etc.
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