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Principal Scientist, Bioanalytical
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- Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RN, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.
- Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45 and 50 skipping amenable.
- You will successfully lead and coordinate bioanalytical support functions across various modalities, including oligonucleotide and biologics modalities, to perform both qualitative and quantitative bioanalysis in complex biological matrices.
- Develop, qualify, and implement bioanalytical assays using LC-MS/MS and ligand binding assay (LBA) to support PK and biodistribution studies for therapeutic candidates including oligonucleotides, biologics, and peptides.
- Oversee bioanalytical deliverables supporting discovery project activities, candidate enabling studies, and clinical candidate IND enabling studies; provide scientific guidance and technical support on method development, qualification, and sample analysis in-house as well as at CROs.
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