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Oligo Data Science Leader
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Full-time
- Oligo Data Science LeaderThe oligotherapy data science leader role is embedded in and directly supports the Oligo Sciences team whose broad remit is the design, characterization, and early development of oligonucleotide therapies.
- Collaborate effectively with renowned GSK experts in genetics, genomics, computational bio & chem, structural biology and medicinal chemistry, artificial intelligence / machine learning, and digital technologies to build the datasets, tools, models, and infrastructure necessary for oligo design & development.
- Java/Rust, or considerable and consistent contributions to an open-source project, or Top10 placement in life-science-themed competitions on Kaggle/TopCoder/DREAM challenge.
- Familiarity with Bayesian statistics and machine learning (ML & DL) with prudent use of suitable methods as projects progress Familiarity with genetic mutations’ impacts on both coding and non-coding RNA sequences and their associated binding proteins, especially in regulating alternative splicing, poly-adenylation, and RNA chemical modifications like methylation or editing.
- Knowledge of 2o and 3o structure and computational/experimental techniques (e.g. Chemical probing, NMR, CryoEM) to determine folding dynamics of eukaryotic RNAs in complex with chaperone RNP and RBPs. Please visit to learn more about the comprehensive benefits program GSK offers US employees.
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