Merck

Core to the Data, AI and Genome Sciences (DAGS) function is an AIML-first approach that leverages massive genetics and genomics data to improving target and biomarker discovery, validation and selection and elucidating complex disease mechanisms.. The Head of Precisions Genetics & Genomics will lead a bioinformatics, genetics, and machine learning team with remit to apply genetic and multi-omic analytics across the drug and diagnostic assay (Dx) development pipeline.. PhD in genomics, genetics, bioinformatics, computational biology, engineering, statistics, or a related field and 8 or more years relevant experience preferred.. Experience in analysis of high-dimensional molecular data, such as single-cell RNAseq, Exome and Whole Genome Sequencing, high-throughput proteomics.. Business Intelligence (BI), Database Design, Data Engineering, Data Modeling, Data Science, Data Visualization, Machine Learning, Project Management, Software Development, Stakeholder Relationship Management

executive director

Job Description Our precision medicine capabilities are critical accelerators to delivering on our mission towards inventing new medicines that save and improve lives. Core to the Data, AI and Genome Sciences (DAGS) function is an AIML-first approach that leverages massive genetics and genomics data to improving target and biomarker discovery, validation and selection and elucidating complex disease mechanisms. The Head of Precisions Genetics & Genomics will lead a bioinformatics, genetics, and machine learning team with remit to apply genetic and multi-omic analytics across the drug and diagnostic assay (Dx) development pipeline. Impact is significant as the head of Precision Genetics/Genomics will be charged with applying and helping to develop core technology needed to analyze massive data for generating critical insights. Decision Making They are responsible for decisions on developing and executing on the scientific and technical strategic roadmap for precisions medicine core to DAGS’s mission to delivering on elucidating mechanisms of disease and improving target discovery, validation and selection. Accountability They will report the Vice President and Head of DAGS. Primary Responsibilities <ul><li>Develop DAGS computationally driven precision medicine scientific and technical strategic roadmap</li><li>Develop and recruit top-notch data scientists with deep computational genetics and genomics expertise</li><li>Apply and build computational/AIML genetics and genomics capabilities and models for analyzing large scale and deep data</li><li>Interface with computational scientists in DAGS to apply capabilities and generate insights across our therapeutic areas</li><li>Interface with FA and TA stakeholders across Discovery, Preclinical, and Translational Medicine (DPTM) to ensure scientific impact and alignment of DTPM goals</li><li>They will oversee a team of up to 20 computational genetics and genomics data scientists </li></ul>Education Minimum Requirements PhD in genomics, genetics, bioinformatics, computational biology, engineering, statistics, or a related field and 8 or more years relevant experience preferred. Required Experience And Skills <ul><li>Minimum 8 years of industry and/or academic experience with significant leadership roles in computational genetics</li><li>Proficiency with at least one high-level programming language (R, Python, C/C++) for complex data analysis and reproducible research practices.</li><li>Expertise in statistical genetics, especially experience with GWAS/QTL integration, Mendelian randomization, and polygenic risk scores, and/or clinical genomics.</li><li>Experience in analysis of high-dimensional molecular data, such as single-cell RNAseq, Exome and Whole Genome Sequencing, high-throughput proteomics.</li><li>Experience in translational / clinical domain including working as part of a matrixed team to address regulatory agency questions and/or feedback</li><li>Background in inflammatory diseases (e.g. autoimmune diseases, IBD, and scleroderma), cardiovascular and metabolic disease, and/or experience working with clinical trial data is a plus </li></ul>Confidential <ul><li>Demonstrated ability of contributing to and helping advance multi-disciplinary team projects.</li><li>Track record of excellent interpersonal and communication skills, including ability to provide concise summaries of complex data to empower decision making.</li><li>Have a strong work ethic and are proactive in providing solutions to foster scientific collaborations and drive projects forward.</li><li>Have ability to work in a highly interactive environment with a diverse team of colleagues </li></ul>NOTICE FOR INTERNAL APPLICANTS In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions. If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor. Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission. Current Employees apply HERE Current Contingent Workers apply HERE US And Puerto Rico Residents Only Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. About We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement Pay Transparency Nondiscrimination We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts U.S. Hybrid Work Model Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”. Under New York State, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education. Expected Salary Range $247,700.00 - $390,000.00 Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here. Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status Regular Relocation: Domestic/International VISA Sponsorship Yes Travel Requirements 25% Flexible Work Arrangements Not Applicable Shift 1st - Day Valid Driving License Yes Hazardous Material(s) n/a Required Skills Business Intelligence (BI), Database Design, Data Engineering, Data Modeling, Data Science, Data Visualization, Machine Learning, Project Management, Software Development, Stakeholder Relationship Management Preferred Skills Requisition ID:R279252

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