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As core member of multi-disciplinary drug discovery teams, you will direct investigative toxicology strategies to predict, assess and mitigate target- and modality-related safety risks in discovery programs, with a focus on Antibody-Drug Conjugates.
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We are seeking a highly motivated Senior Scientist who will contribute to the discovery of novel oncology medicines that include T Cell Engagers and Antibody Drug Conjugates for haem and solid tumor indications.
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Demonstrates expertisein the utilization of the mouse as a platform of basic biomedical and drug discovery research and in the service solutions provided by the Jackson Laboratory to solve research problems while competitively differentiate JMCRSs solutions.
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy, and Epigenetics) to help address unmet clinical needs in a host of cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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Prior experience in drug discovery and development, particularly in the field of immuno-oncology, is preferred but not required. The successful candidate will play a pivotal role in advancing the immuno-oncology pipeline, contributing to the discovery and development of novel immunotherapies for the treatment of cancer.
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This is your chance to join our Tumor Targeted Delivery team in Early Oncology in Gaithersburg, MD USA. As a Senior Scientist, you will lead target validation efforts for tumor-targeted therapies, such as antibody-drug-conjugates (ADCs) and targeted radio-conjugates.
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Strong understanding of pharmacokinetics, biomarkers, statistical principles, and regulatory requirements and demonstrated experience integrating these disciplines in the context of drug development.
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Independently conducts in vitro immunologic drug discovery experiments by applying techniques of molecular and cellular biology. Assesses and reports data, with little or no guidance, in a clear and concise manner, with a clear understanding of its implications within the overall context of drug discovery.
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Cancer biology, immunology, molecular biology, bioinformatics) with 0-2 years’ experience in drug discovery or drug development. Plan, design, and execute IND-enabling pharmacology, pharmacokinetic and toxicology studies by applying knowledge of disease-associated pathways, preclinical models, and drug development.
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Experience specifically supporting drug discovery research and development from a toxicology standpoint. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global health security; and HIV/AIDS programs.
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Drug discovery experience in a biotech or pharmaceutical environment is preferred (large or small molecules, understanding of drug properties, assay/model development) in particular experience working with large molecule-based therapies.
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The company is led by experienced academic, biopharma and CDMO entrepreneurs with expertise in drug discovery, product development, characterization and testing. Deka is currently seeking an Analytical Development Associate Scientist with experience in analytical methods, HPLC, cIEF, CE-SDS, potency assays.
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The ASPIRE Initiative aims to formulate a framework which integrates Automated Synthetic Chemistry (ASC), Artificial Intelligence (AI) / Machine Learning (ML), and Automated Biological Annotation (ABA) into a modular research platform that accelerates preclinical drug discovery across a wide range of human diseases and conditions.
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The Biologics Engineering team is responsible for the discovery and optimization of next generation biological drug candidates for all key therapy areas across AstraZeneca, and for developing in-house biologics discovery platforms and Client drug modalities to address unmet medical needs.
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drug discovery jobs in Rockville, MD
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