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Liaise with drug discovery, pharmacology, research and toxicology as necessary in order to finalize a pre-clinical program which will permit the most efficient clinical development of new chemical entities within the framework of the project team.
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Provides scientific and clinical input to study-related documents and analysis plans including Informed consent forms (ICF), clinical research forms (CRF), statistical analysis plans (SAP), clinical pharmacology and biomarker analysis plans.
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Job Overview: The in vivo pharmacology group is currently seeking a highly motivated and scientifically rigorous Research Associate or Associate Scientist to execute in vivo studies and ensure proper care of research animals, while also sharing their passion for finding a lasting cure for patients.
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Takeda Development Center Americas, Inc. is seeking a Senior Manager, Clinical Data Management in Lexington, MA with the following requirements: Master’s degree in Pharmaceutical Sciences, Pharmacology or Toxicology or related field or foreign academic equivalent plus 6 years of related experience.
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QP2-IO team is part of the Global Clinical Development organization and has oversight over drug development aspects related to clinical pharmacology and pharmacometrics of oncology drugs from post-PCC to registration.
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Partners with CMC, Clinical Development, Clinical Operations and Pharmacology to ensure GMP, GLP and GCP compliance for all clinical development programs by providing guidance. Oversees the QA reviews of GMP manufacturing batch records, product release and stability testing, validation reports, pharmacology and toxicology study reports and essential clinical study documents.
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Research Associate / Sr. Research Associate of in vivo Pharmacology. Research Associate / Sr. Research Associate of in vivo Pharmacology. Proficient in standard in vivo techniques (animal handling, blood collection, dosing (SQ, IV, IM, and IP), necropsy, tissue dissections.
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20+ years of progressive relevant experience within the biopharmaceutical/biotech industry in translational medicine/biology, clinical pharmacology or directly related discipline, preferably in the biopharmaceutical/biotech industry.
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Hands-on experience establishing and optimizing in vivo pharmacology models and assays. PhD or MSc (with equivalent experience) in a relevant field (e.g., Biology, Biochemistry, Pharmacology, Toxicology, Engineering, Physics.
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The candidate will have the opportunity to lead multi-disciplinary drug discovery and preclinical teams as targets progress and will be expected to work seamlessly with colleagues across discovery research, chemistry, preclinical pharmacology, toxicology and analytical development.
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Relying on advanced training in psychodynamics, pathophysiology, physical assessment, pharmacology, treatment intervention, addictions management, harm reduction, and relapse prevention, the APRN provides an assessment and assistance with establishing comprehensive plans that address a broad range of concerns for the patient with behavioral health and substance abuse disorders.
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Supervise the execution of pharmacology studies at CROs and perform in-house downstream analysis to support drug discovery program needs. This candidate will play an active role in animal model development for pharmacology studies to address biological hypotheses.
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Strong understanding of all aspects of compound optimization including synthetic chemistry, structure-based drug design, ligand-based drug design, pharmacokinetics, pharmacology, and toxicology.
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Required: M.S. with 5+ or Ph. D with 2-4+ years of applicable industry experience in Immunology, Cell Biology, Pharmacology, Pharmaceutical Science, or other relevant disciplines. Blood cell isolation, flow cytometry, Luminex profiling, ELISA, immunohistochemistry (IHC), confocal microscopy, and any other related common immunology tools/assays.
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MLAB Biosciences is seeking a motivated Research Associate contractor to join the in vivo pharmacology team to help advance our therapeutic programs. In addition to supporting in vivo dosing studies and related research activities, s/he will be responsible for executing experiments to quantify molecular, cellular, and physiological readouts within the in vivo pharmacology group.
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pharmacology job in Cambridge, MA
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