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You will be the drug metabolism and pharmacokinetics (DMPK) lead on project teams discovering and developing small molecule modulators of clinically meaningful targets. Work closely with DMPK CROs to design, coordinate, monitor and manage external ADME and PK studies.
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Quantitative Systems Pharmacology (QSP) & Physiologically Based Pharmacokinetics (PBPK) have become important components of discovery and clinical development. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources.
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The scientist will collaborate with biologists and data analysts across diverse therapeutic areas, such as Oncology, Immunology, Infectious Diseases & Vaccines, Neuroscience, and Pharmacokinetics.
$122,800 - $193,300 a yearExpandUpdated 4 days ago - UpvoteDownvoteShare Job
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Solid working knowledge of Pharmacokinetics, PK/PD principles applied to modeling, ADME and clinical pharmacology concept and understanding of regulatory guidelines on DMPK/ clinical pharmacology studies to support early oncology drug development.
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MSc or PhD in Drug Metabolism, Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, or related disciplines. Planning, stewardship, analysis, and integration of all in In Vitro and In Vivo ADME, PK, and PK/PD efforts in support of discovery and preclinical development programs.
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MS or PhD in pharmacokinetics, chemistry, biochemistry, or a related scientific discipline required. MS or PhD in pharmacokinetics, chemistry, biochemistry, or a related scientific discipline required.
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Working knowledge of drug development, clinical research, study design, biostatistics, pharmacokinetics, the regulatory environment, and medical terminology. Working knowledge of drug development, clinical research, study design, biostatistics, pharmacokinetics, the regulatory environment, and medical terminology.
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D. or equivalent training in pharmacokinetics, pharmaceutical sciences, or related disciplines with 5 years of clinical pharmacology industry experience or M.S. with 10 years of relevant experience.
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Partner with other disciplines of integrated drug discovery and development, especially pharmacokinetics and drug disposition, Drug Safety, Regulatory, and Translational Sciences, to develop translational preclinical packages for gene therapy clinical candidates.
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And as the premier supplier of hepatic products, including hepatocytes and subcellular fractions, BioIVT enables scientists to better understand the pharmacokinetics and drug metabolism of newly discovered compounds and their effects on disease processes.
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The Drug Metabolism and Pharmacokinetics (DMPK) department provides ADME/DMPK, as well as translational PKPD Modeling & Simulation support to our portfolio. The Drug Metabolism and Pharmacokinetics (DMPK) department provides ADME/DMPK, as well as translational PKPD Modeling & Simulation support to our portfolio.
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This role involves spearheading the design and implementation of both in vivo and ex-vivo pharmacology studies, critically contributing to our understanding of the pharmacokinetics/pharmacodynamics (PK/PD), target engagement, and therapeutic efficacy of our novel drug candidates.
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Subject matters may include dosage forms and drug design, pharmaceutical calculations, pharmacokinetics, pharmaceutical analysis, physical pharmacy and controlled drug delivery. Subject matters may include dosage forms and drug design, pharmaceutical calculations, pharmacokinetics, pharmaceutical analysis, physical pharmacy and controlled drug delivery.
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This is a Programmer Analyst II role within our Pharmacokinetics department, in which this role can be a fully remote role. This is a Programmer Analyst II role within our Pharmacokinetics department, in which this role can be a fully remote role.
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We are a dynamic clinical-stage biotechnology company dedicated to addressing both prevalent and rare autoimmune diseases such as celiac disease, multiple sclerosis, and type 1 diabetes.
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pharmacokinetics job in Cambridge, MA
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