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Here's What You'll Do:Lead right-first-time cGMP manufacturing of cell and gene therapy products including but not limited to aseptic processing, cell isolation, selection, culturing, cryopreservation, upstream processing, downstream processing, aseptic fill finish and final product visual inspection.
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Research experiments will encompass cell culture process development, media development, bioreactor scale-up, cell banking activities and execution of quantitative biological assays.
$30 an hourExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Knowledge of laboratory and pharmaceutical production equipment including but not limited to autoclaves, process tanks, cell culture equipment, chromatography skids and columns, analytical equipment.
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The role will lead sound experimental design to develop bioreactor cell culture, cell processing and harvest unit operations for an allogenic stem cell therapy product. Scale-up stem cell islet DS process including bioreactor cell culture, media optimization, filtration and harvest process from clinical to commercial scale.
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Director/Sr. Director - Process DevelopmentGreater Boston Area Competitive Compensation + excellent bonus/benefitsDuties and Responsibilities:Lead all process development activities (cell culture/banking/development, fermentation, protein purification, tech transfers)Oversee internal(in-house) and external vendors (domestic & international CDMOs)Work cross-functionally with CMC & Manufacturing leaders such as Analytical, Drug Product, QA/QC, Manufacturing, Supply Chain, etc.
$210,000 - $240,000 a yearExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Serving as a technical/scientific Subject Matter Expert primarily for upstream cell culture/fermentation activities ranging from vial thaw, inoculum, media development, media optimization, cell line development and stainless steel bioreactor operations.
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Manage cell line development, clone selection/stability, upstream/downstream development and manufacturing operations at the CDMOs∯*∯ Expertise in cell culture, media and bioreactor optimization with an emphasis on scale-up, scale-down models, process monitoring, facility fit and overall commercial readiness.
$225,000 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Upstream cell culture or downstream purification experience. Job Title: Process Engineer/Upstream or Downstream. Develop and maintain process control automation solution for bench top Finesse and DeltaV Controllers systems in Next Generation Lab.
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Broad experience in the application of biochemical, biophysical & cell-based techniques such as Western blotting, plate-based enzyme assays, RNA/DNA extraction and QC, PCR, probe-based qPCR and dPCR, gel electrophoresis and EMSA, in vitro transcription, mammalian cell culture and transfections.
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Experience with cell culture technologies, molecular biology, upstream processing and aseptic processing preferred. In this role, the Downstream Process Development Scientist II/III will provide technical expertise and leadership in science and technology while closely collaborating with internal teams.
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We are seeking a highly motivated and experienced Account Manager responsible for selling the expanding portfolio of highly differentiated upstream and downstream processing solutions that address critical steps in the development and production of biologic drugs – principally in the rProtein, mRNA and Cell & Gene Therapy segments - to new and existing customers across a territory spanning the greater Boston area.
$160,000 a yearFull-timeExpandApply NowActive JobUpdated 11 days ago - UpvoteDownvoteShare Job
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Proficient in cell culture and cell imaging, such as stable cell line generation and maintenance, high content imaging or flow cytometry. Actively participate in project teams by communicating experimental results and advising on best methods to generate protein reagents for downstream applications including but not limited to biophysical characterization, immunization, assay development, screening and hit identification.
$126,630 a yearFull-timeExpandApply NowActive JobUpdated 13 days ago - UpvoteDownvoteShare Job
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Strong understanding of upstream and downstream bioprocessing technologies, including cell culture, purification, and bioreactor systems. Strong understanding of upstream and downstream bioprocessing technologies, including cell culture, purification, and bioreactor systems.
$150,000 a yearFull-timeExpandApply NowActive JobUpdated 11 days ago - UpvoteDownvoteShare Job
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Instrumentation background, preventative maintenance, automation background (DeltaV or Finesse controllers), and process monitoring or trending experience. Business Unit: Pilot Plant. Initiating review and approval of changes to operating procedures and EHS change control process relating to the system.
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The incumbent will work at the bench to develop production cell lines, establish and maintain working cell banks and RCBs, and optimize cell culture conditions for TCR bispecifics and MHC proteins, as well as extraction methods for inclusion bodies.
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downstream cell culture jobs in Boston, MA
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