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The ideal candidate would have extensive experience in cell line and upstream process development. We are working to develop and implement initiatives that promote diversity, equity, and inclusion throughout the organization and foster a culture of openness, respect, and collaboration, where all voices are heard, and everyone is valued for their unique perspectives and contribution.
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Subject matter expertise in mammalian cell culture; with familiarity in downstream/purification operations and alternative modalities including microbial fermentation or viral vector production.
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Experience in mammalian cell culture and ex vivo assays, such as Western blotting and qPCR. Experience maintaining cell lines in tissue culture, preparing reagents and dosing solutions.
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The ideal candidate should have extensive experience in a cGMP Manufacturing cleanroom environment, demonstrated prowess in cell therapy manufacturing, prior supervisory experience, and enjoy fast-paced, collaborative, and vibrant startup culture.
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Must have experience in aseptic techniques including, but not limited to the culture of human cell lines, primary tissue culture and long-term cultures. Stem cell related research experience including long term culture maintenance also highly desired.
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In addition to basic methods of cell and molecular biology including signal transduction pathways, microRNA and long noncoding RNA, transgenics and gene knock out the Chen Lab has used a number of rodent animal models, in which stem cells, growth factors and advanced matrix scaffolds are applied.
$47,800 - $71,900 a yearFull-timeExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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The candidate will support advancement of innovative AAV-based therapeutics through development and execution of a variety of research methods including molecular and biochemical techniques, mammalian cell culture, and cell-based assays.
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Supervised by the PET Core Directors, the preclinical research lab manager will be an integral participant in the day-to-day operations of a research laboratory, assisting with all routine aspects of the project including animal handling, cell culture, and isotope use.
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Job Requirements REQUIRED: bachelor’s degree in biology, neuroscience, or related field; two years' related experience, including at least one year of cell culture experience; excellent sterile technique; and the ability to work both independently and as part of a team.
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The company focuses on producing cell culture products, instruments, and solutions that help customers streamline their discovery, development, and production processes, and by making custom cGMP bioprocess liquids that radically simplify customers' manufacturing workflows - regardless of batch size.
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This includes cell-based assays, tissue culture, biochemical assay technologies, and protein and RNA expression analysis. Experience with cell culture and in vitro assays is desirable.
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Establishing in vitro assays to evaluate efficacy, dose response relationships, and characterizing molecules for potential therapeutic effects via techniques including cell culture, qPCR, transfection, transduction, cholesterol measurement, RNA expression analysis, and general molecular biology.
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Technical expertise with in vitro and ex vivo assays, mammalian tissue culture, reporter cell lines (including custom generation of reporter systems), and primary human cell cultures.
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Tissue culture techniques and functional cell-based assay development. OR BS Degree and 10+ years of experience in antibody engineeringLine management and or laboratory managementMolecular and cell biology techniques, including; cloning, transfection and transduction methods.
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Hands on experience with mammalian cell culture, ELISA and flow cytometry is required. The key functions for this lab-based role is to perform cell-based experiments to assess the performance of our novel RNA molecules and to conduct the end-point assays for various in vivo experiments (e.g. ELISA, MSD, flow cytometry.
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cell culture jobs in Boston, MA
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