Senior Machine Learning Engineer

OverviewJob DescriptionSenior Machine Learning EngineerCompany: Hologic Inc.Location: Newark, DESanta Clara, CA | Newark, DE | Remote (US)Job Type: Full-timeSalary: $102.20K - $140.30K/yr (Estimated pay)Role SummaryAs a Senior Machine Learning Engineer within Hologic\'s Breast & Skeletal Health division, you will design, develop, and deploy advanced AI algorithms for nextgeneration medical imaging devices. A key focus of this role is building and validating AI-driven solutions for breast cancer detection in breast tomosynthesis (3D mammography). Your work will directly impact patient outcomes by ensuring our AI solutions are accurate, robust, safe, and clinically validated, supporting Hologic\'s mission to improve women\'s health through innovative, highquality technologies.ResponsibilitiesDesign and develop ML/AI models for breast imaging, with a focus on digital breast tomosynthesis (DBT) and related modalities.Own the endtoend ML pipeline: data preparation, feature engineering, model training, evaluation, deployment, and monitoring in production environments.Work with largescale medical imaging datasets, including DICOM images, to build highperforming and reliable models.Implement and optimize deep learning architectures (e.g., CNNs and related vision models) for detection, classification, and related tasks in breast imaging.Validate and benchmark models using appropriate metrics, crossvalidation, test sets, and clinically relevant performance measures.Collaborate with crossfunctional teams (engineering, clinical, regulatory, and product) to translate clinical needs and business requirements into robust ML solutions.Contribute to design and documentation needed for regulatory submissions and clinical validation, following FDA and other relevant guidelines for AI in healthcare.Ensure code quality and reliability, applying good software engineering practices (testing, version control, code reviews, documentation).Mentor junior engineers and scientists, sharing best practices in ML, deep learning, and software development.Required QualificationsExperience: 5+ years of handson experience in machine learning, applied AI, or ML engineering, ideally with exposure to computer vision or medical imaging.Education: Bachelor\'s degree in a related field preferred (e.g., Computer Science, Electrical/Computer Engineering, Data Science, Mathematics, Statistics, Biomedical Engineering, or similar). Advanced degree (Master\'s or PhD) is a plus but not required.Technical Skills:Strong understanding of machine learning and deep learning principles, including supervised learning and, ideally, selfsupervised or semisupervised methods.Solid knowledge of neural network architectures and training techniques, particularly for computer vision (e.g., CNNs, modern vision architectures).Foundation in computer vision techniques, data preprocessing, feature engineering, and statistical analysis.Experience with model validation and performance benchmarking, including selecting appropriate metrics and designing experiments.Strong programming skills in Python (required); C++ experience is a strong plus.Proficiency with ML/data science libraries and tools such as NumPy, SciPy, Pandas, OpenCV, scikitlearn, XGBoost.Handson experience with deep learning frameworks such as PyTorch and/or TensorFlow.Experience designing and implementing scalable ML pipelines, including training, inference, and monitoring.Experience with cloud platforms (e.g., AWS, Azure, or GCP) for training and/or deploying ML models.Familiarity with software engineering best practices, including modular design, testing, debugging, version control (e.g., Git), and CI/CD concepts.Familiarity with software engineering best practices and hands-on experience with AI/ML in healthcare development environments.Preferred / Bonus QualificationsFamiliarity with the DICOM format and medical imaging workflows, ideally including digital breast tomosynthesis (DBT).Understanding of breast cancer pathology, radiology workflows, and how mammography is used in clinical practice.Experience working under FDA regulatory standards or similar frameworks for AI/ML in healthcare, including validation protocols, documentation, and risk management.Experience contributing to regulated medical device software or products subject to 510(k)/PMA submissions.Exposure to MLOps practices and tools (e.g., MLflow, Kubeflow, SageMaker, model monitoring, experiment tracking).Soft Skills & BehaviorsAbility to translate complex technical concepts into clear language for clinical, product, and business stakeholders.Strong problemsolving skills and a practical mindset focused on delivering reliable, realworld solutions.Demonstrated ability to work independently while also collaborating effectively in crossfunctional teams.Experience mentoring or guiding junior team members and contributing to team standards and best practices.High level of ownership, attention to detail, and commitment to quality, especially given the impact on patient care.J-18808-Ljbffr