Scientific Associate Director PKDM (Small Molecule ADME) - CA

Minimum Education Required: BachelorsScientific Associate Director - PKDM (Small Molecule ADME)Our award‐winning culture is collaborative, innovative, and science‐based. If you have a passion for challenges and the opportunities that lie within them, you will thrive as part of the Amgen team. Join us and transform the lives of patients while advancing your career.Job DescriptionWe are looking for a subject‐matter expert in small molecule biotransformation to oversee ADME and PK activities, support small molecule (SM) programs, and lead projects as a functional PKDM project team representative.ResponsibilitiesLead biotransformation activities to support SM programs and develop strategies to mitigate metabolism risks.Leverage current biotransformation knowledge and develop/implement novel tools to support related activities.Serve as a functional PKDM project team representative and subject‐matter expert on ADME/PK of small molecule therapeutics, collaborating across the PKDM scientific community.Apply specialized ADME/PK skills (in vitro ADME, in vivo ADME, biotransformation, PK/PD, PBPK) to impact project progression and decision‐making.Plan and execute mechanistic ADME/PK analyses to integrate drug‐design, disease pharmacology, physiology, PK, and PD for optimal dose selection and preclinical study designs.Contribute to the analysis of pre‐clinical ADME and PK data for IND and NDA filings, documenting analyses in reports.Build close relationships with partner functions and therapeutic areas.QualificationsBasic QualificationsDoctorate degree (PhD, PharmD, MD) with relevant post‐doc and 4 years of directly related experience, ORMaster's degree with 7 years of directly related experience, ORBachelor's degree with 9 years of directly related experience.Preferred QualificationsPhD in Pharmacokinetics, Pharmaceutical Sciences, Engineering, or related fields with 10+ years of experience in the biotechnology/pharmaceutical industry, consulting, or post‐doctoral training.Solid technical experience applying SM in vitro/in vivo ADME and pharmacokinetics fundamentals to drug discovery projects.Ability to drive SM discovery and development within project teams.Establish SM biotransformation and ADME workflows for PKDM scientists.Expertise with in vitro ADME, in vivo ADME, PK/PD, or PBPK.Experience supporting preclinical components of regulatory documentation.Excellent interpersonal, technical, and communication skills to lead cross‐functional teams.Past experience as a laboratory scientist in a pharma or biotech environment.Excellent written and oral communication skills, attention to detail, and interpersonal skills.Record of scientific contributions through peer‐reviewed articles and external presentations.BenefitsCompetitive base salary, with total rewards including health, welfare, and retirement plans.Discretionary annual bonus program and stock‐based long‐term incentives.Award‐winning time‐off plans.Flexible work models, including remote and hybrid arrangements where possible.Application InformationApply now and make a lasting impact with the Amgen team. Visit careers.amgen.com. Amgen does not have a fixed application deadline; we will continue accepting applications until we receive a sufficient number or select a candidate.Pay Range: South San Francisco: $216,073 - $255,336; Thousand Oaks: $202,013 - $227,352.#J-18808-Ljbffr