Senior Manager Translational Scientist (Cardiology & Cell Therapy)

Manager / Senior Manager, Translational Science (Cardiology & Cell Therapy)Dallas, Texas, United States (Remote)Hartmann Young are partnering with a fast‑growing, privately held biotech advancing a novel cell‑based therapeutic platform for cardiovascular disease, with a primary focus on cardiomyopathy and heart failure. The company operates as a lean, highly scientific organization, offering individuals significant ownership across translational and early clinical development.This is a high‑impact Manager / Senior Manager‑level role for a translational biologist who brings deep in vivo expertise, strong study‑design capability, and the adaptability to work across indications in an evolving pipeline. The role is remote across the U.S., with Dallas / Plano–based candidates strongly preferred given the company’s growing presence in Texas and future laboratory plans.This is an urgent hire at a critical development inflection point.The RoleYou will play a central role in shaping and executing the company’s translational strategy, bridging mechanistic biology, nonclinical modeling, and early clinical development. While cardiology experience is highly desirable, the role is intentionally broad and suited to someone with a cell therapy background beyond oncology, such as autoimmune, regenerative medicine, or adjacent therapeutic areas.This position requires someone who has personally designed and executed in vivo studies and can now apply that experience strategically in a leadership role.Key ResponsibilitiesProvide scientific leadership across translational biology activities supporting programs from preclinical through early clinical development (Phase 1/2)Design, oversee, and interpret in vivo and in vitro studies, including nonclinical efficacy, mechanistic, and PK/PD workServe as a subject‑matter expert in animal models relevant to cardiomyopathy, heart failure, and related non‑oncology indicationsTranslate preclinical findings into:Clinical hypothesesBiomarker and translational strategiesDose and regimen rationaleSupport IND‑enabling activities, including contribution to translational sections of regulatory submissionsAuthor and review key program documents such as:Nonclinical study reportsInvestigator’s BrochuresTranslational components of protocolsManage and collaborate with CROs, academic partners, and external vendors, including oversight of timelines and data qualityPartner cross‑functionally with Clinical Development, Regulatory, Biometrics, and OperationsSupport interpretation of emerging clinical data in the context of preclinical and translational evidenceOperate effectively in a resource‑lean, high‑ownership biotech environmentExpertise We’re Looking ForRequired:Extensive hands‑on in vivo experience gained through graduate training and/or industryCandidates must have personally designed and executed animal studies, even if day‑to‑day bench work is no longer central to their roleStrong background in translational biology, including study design, execution, and interpretationExperience managing or partnering with external CROsComfortable working across multiple scientific approaches and indicationsHigh scientific rigor, adaptability, and intellectual curiosityStrongly Preferred:Experience in cardiology (e.g., cardiomyopathy, heart failure), or adjacent non‑oncology therapeutic areas (e.g., neuro, autoimmune)Cell therapy experience outside of oncology (e.g., autoimmune, regenerative medicine, stem‑cell–based platforms)Familiarity with non‑tumor models, as this will not be an oncology‑focused companyExposure to IND‑related or IND‑enabling researchExperience in small biotech or early clinical development environmentsEducation:PhD preferred, but a Master’s degree with extensive, relevant translational and in vivo experience will be consideredPersonal Profile:High‑quality performer with a strong work ethic and ownership mindsetAdaptable, eager, and comfortable operating in ambiguityAble to clearly discuss multiple indications and scientific philosophiesDoes not need to be highly “validated,” but must be confident and credible across translational disciplinesComfortable with the pace and breadth of responsibility typical of an early‑stage biotechWhy Join?Join a mission‑driven biotech addressing high‑unmet‑need cardiovascular diseasesSignificant hands‑on scientific ownership with real influence on program directionExposure to a dynamic, cell‑therapy platform with relevance beyond a single indicationFlat organizational structure with high visibilityRemote U.S. role, with added opportunity for impact if Dallas‑based