Chief of Staff to the CEO

Role SummaryWe are seeking a Chief of Staff to report directly to and support our CEO in key elements of operations and strategy. You'll have direct access to a CEO building at the frontier of AI and drug discovery, at a company with real scale ($300M+ raised, pharma partnerships, an internal pipeline) and real ambition.As a Chief of Staff to the CEO, you'll be at the center of how Genesis operates and where it's going. That means owning the systems that keep the leadership team aligned - quarterly and annual planning, board meeting preparation, exec team facilitation - while also acting as the CEO's trusted voice in internal and external communications.What You'll Do* Provide thought partnership to our leaders. You'll work closely with the CEO and leadership team to drive strategic decisions and contribute to company strategy* Be a force multiplier. You'll take on strategic work directly on behalf of the CEO, owning ad-hoc strategic projects that require pulling together resources and perspectives across the organization* Keep a pulse on the business. You'll meet regularly with teams across the company to surface headwinds, identify inefficiencies, and connect dots that leaders embedded in their functions can't easily see* Drive strategy and operating rhythm. You'll be a thought partner on company strategy and own the systems that keep the leadership team aligned and moving: quarterly and annual planning, OKR setting, exec team meetings, and board meeting preparation* Lead cross-functional initiatives. You'll take on strategic projects that don't fit neatly into one function - the kind of work that falls through the cracks without someone owning it with both breadth and urgency.Who You AreYou are someone who gets things done. You're equally comfortable in a spreadsheet, a board deck, and a conversation with a skeptical executive. You bring analytical rigor and good instincts, and you know which one to lean on when.Specifically:* Sharp and intellectually curious. You bring genuine strategic judgment and analytical horsepower. You can go deep on a technical whitepaper in the morning and a go-to-market framework in the afternoon.* Execution-oriented. You thrive in ambiguity and drive projects from unclear starting point to clear outcome. You don't let things stall.* Low ego, high ownership. You take pride in making others - especially the CEO - more effective. You don't need the credit.* Excellent communicator. You write and speak with clarity and precision. You can present to the Board, synthesize a messy situation into a crisp memo, and know the difference between the two.* Trusted operator. You understand the weight of being in the room where decisions get made, and you handle sensitive information with discretion and judgment.What You'll Bring* 3-5 years of experience in a role that sharpened your analytical and operational instincts: top-tier management consulting, venture capital, or business operations at a high-growth technology or biotech company. Experience at or with a technology company, especially in AI, software, or data-driven environments, is a strong plus and reflects the kind of candidate who will thrive here.* Direct experience working across functions under real pressure: you've shipped something, owned something, or solved something that mattered* Strong executive communication skills, written and verbal, with demonstrated ability to influence senior stakeholders* Bachelor's degree required; MBA or other advanced degree from a top institution is preferred. A PhD or other advanced degree in a STEM field is also welcome.* Candidates based in the Bay Area are preferred; ability to travel domestically and internationally ~10% of the timeAbout Genesis Molecular AIGenesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company's generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets.Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.