Executive Director Process Chemistry

Tyra Biosciences, Inc. is seeking a highly qualified Executive Director of Process Chemistry to lead the development, optimization, and scale-up of small molecule drug substances from early development through commercialization. This role provides technical and operational leadership across process development, manufacturing, and regulatory activities while managing internal teams and external partners. Essential Functions and ResponsibilitiesTechnical Leadership:Lead process development, optimization, and scale-upOversee impurity control and ICH M7 strategiesSupport process validation and control strategiesAuthor and review CMC sections for regulatory submissionsManufacturing & CDMO Oversight:Manage CDMO relationships and manufacturing campaignsSupport tech transfer and scale-up activitiesReview deviations, investigations, and batch recordsRegulatory & Quality:Support IND, NDA, and MAA filingsEnsure compliance with ICH guidelinesParticipate in inspections and auditsLeadership:Lead and develop process chemistry teamsManage project timelines and budgetsCollaborate cross-functionally across CMC disciplinesEducation & ExperiencePhD in Organic Chemistry or related field15+ years of experience in process chemistryExperience advancing at least one program to commercializationStrong knowledge of GMP and regulatory requirementsLate-stage drug development experience on multiple trials (P3) required, through commercialization preferred.Experience working in a fast-paced, agile working environment. Biotech experience preferred.Strong communication skills, including formal presentations and informal scientific discussions, with internal and external stakeholders and experts.Flexibility and adaptation to demanding timelines.Team oriented person.Fluent in spoken and written English.Technical experience and familiarity with software programs and databases used by CROs and other organizations. Highly detailed with strong organization skills.Up to 25% travel, including some international travel, may be required.Pay Range and BenefitsBase Salary Range: $282,134 - $305,026 USDIndividual compensation will be determined based on factors such as work location, skills, education, training, and experience.What we offer US-based Employees:Competitive base, bonus, new hire and ongoing equity packagesThe starting compensation range(s) for this role is for a full-time employee (FTE) basisBenefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollmentEmployer-paid Medical, dental, and vision insuranceEmployer-paid life insurance, AD&D, short-term disability, long-term disability, and EAP coverage401(k) Plan with a fully vested company match 1:1 up to 4% of contributionsEmployee Stock Purchase Plan14 -18 paid holidays, including office closure between December 25th and January 1stFlexible vacationSick timeFitness ProgramGet Outdoors ProgramPaid parental leave benefitTuition assistanceJob Type: Full-TimeWork authorization: United States (Required)Work Location: RemoteEqual Opportunity Employer: Tyra Biosciences, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.Notice to Recruiters and Third-Party Agencies: The Talent Acquisition team manages the recruitment and employment process for Tyra. To protect the interests of all parties involved, Tyra will only accept resumes from a recruiter once a fully executed search agreement is in place. Agencies are hereby specifically directed not to contact Tyra employees directly in an attempt to present candidates. Tyra will consider any candidate for whom an Agency and/or Recruiter has submitted an unsolicited resume to have been referred, free of any charges or fees.