Supply Planning Manager

Job Title: Supply Planning ManagerLocation: Boston, MADuration: 12 Months (Possible Extension)Job Description:The Manager, Supply Planning is embedded within Client's External Manufacturing organization. This individual will own the end-to-end supply planning function for Verve Therapeutics' clinical programs, operating in a fully outsourced CDMO model built on mRNA/LNP technology. The role is foundational to the team's S&OP process design and will serve as the primary driver of 18-month rolling MRP for clinical drug product supply.KEY RESPONSIBILITIES:Supply Planning & MRP:Develop and maintain rolling supply plans for clinical drug productGenerate forward-looking material requirements for drug substance intermediates and critical excipientsManage supply plan assumptions, risk scenarios, and inventory coverage Clients in alignment with program timelinesS&OP Process Development:Build and maintain S&OP templates, KPIs, and reporting dashboardsPrepare and present supply plan summaries for cross-functional leadership reviewsCDMO Network Coordination:Translate supply plans into manufacturing schedules coordinated across external CDMOsMonitor schedule adherence, batch release timelines, and supply risk through collaborative CDMO governanceMaintain material genealogy and lot traceability across the multi-step supply chainRisk & Inventory Management:Develop safety stock strategies for critical materials, accounting for CDMO lead times, shelf-life/expiry constraints, and clinical trial uncertaintyIdentify and escalate supply risks with mitigation options framed for leadership decision-makingSupport annual reportable change and regulatory change management (Client) from a supply continuity standpoint QUALIFICATIONS:Required:Bachelor's degree in Supply Chain, Engineering, Life Sciences, or related field; advanced degree a plus5+ years of supply chain or supply planning experience in pharmaceutical, biotech, or CDMO environmentHands-on experience with MRP/ERP systems (SAP strongly preferred)Direct experience with clinical supply planning in an outsourced manufacturing modelStrong analytical skills; proficiency with supply planning tools and Excel/dashboard platformsPreferred:Experience with advanced therapy or biologic modalities (LNP, mRNA, gene therapy, oligonucleoProduct)Familiarity with S&OP/IBP process design and implementationExposure to Client regulatory requirements (IND-stage) and supply risk classificationAPICS CPIM or CSCP certification