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Scientist

Title: NGS ScientistLocation: Boston, MA contract: 6-Month ContractWe are seeking an experienced NGS Scientist to join a leading Cardiometabolic Research team focused on advancing therapies for diabetes, obesity, cardiovascular disease, and metabolic disorders. This role will support cutting-edge sequencing workflows and collaborate across multiple therapeutic areas within a fast-paced research environment.Key ResponsibilitiesPerform NGS library preparation workflows including bulk RNA-seq, scRNA-seq, and snRNA-seqExecute sequencing, quantification, QC analysis, and sample preparation activitiesDevelop and optimize new NGS workflows to support evolving research needsMaintain SOPs and ensure consistent delivery of high-quality sequencing dataCollaborate cross-functionally while managing multiple sequencing requests and timelinesHandle inventory management for RNA/DNA samples, libraries, and sequencing reagentsSupport additional molecular biology tasks including RNA extraction, qPCR, and ddPCRMaintain accurate experimental documentation using electronic lab notebooks (ELN)Assist in evaluating sequencing workflows across partner sites and CROsRequired QualificationsB.S. or M.S. in Biology, Molecular Biology, Biochemistry, or related scientific field3–5 years of hands-on laboratory research experienceStrong background in NGS technologies and their applications, including quantification, sequencing, and data QC (preferably Illumina). Direct experience with RNA-seq (bulk) and amplicon-seq.Direct experience with single-cell and single-nucleus RNA-seq library preparation is required. Candidates must be familiar with multiple scRNA-seq/snRNA-seq platforms (e.g., 10X Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences). Additional Skills/Preferences: Familiarity with CRISPR-based gene editing and high-throughput screening is a plus.Experience with automation is a plus (Mantis, Integra systems, Liquid Handlers, SPTLabtech Firefly, Tecan, etc).Strong organizational, time management, and communication skills.Experience with documentation in electronic notebook software.

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