Senior Clinical Trial Manager

Senior Clinical Trial ManagerThe Senior Clinical Trial Manager provides strategic and operational leadership for global clinical programs, with a focus on renal denervation (RDN) and cardiology clinical trials. This role leads Clinical Trial Managers and study teams to ensure successful planning, execution, and delivery of clinical studies in alignment with program strategy, timelines, budget, quality standards, and regulatory requirements.This position plays a critical role in driving clinical excellence, managing vendor performance, and ensuring inspection readiness across the full lifecycle of clinical trials.Key ResponsibilitiesLead, mentor, and develop Clinical Trial Managers and study personnel, fostering a high-performing and collaborative team environmentOversee end-to-end execution of global clinical trials, ensuring compliance with protocols, GCP, SOPs, and regulatory requirementsTranslate program strategy into operational plans, timelines, and resource allocationsEnsure cross-functional alignment and timely achievement of study milestonesOversee development and maintenance of study documentation, including operational plans, study materials, and regulatory submissionsManage CROs and external vendors, including selection, contracting, performance oversight, and issue escalationMonitor and manage clinical trial budgets, including forecasting, accruals, and variance analysisIdentify risks proactively and implement mitigation and contingency plansProvide clear, data-driven updates, risk assessments, and recommendations to leadership and governance teamsBuild and maintain strong relationships with investigators, clinical sites, and key opinion leaders to support enrollment and engagementEnsure inspection readiness and compliance with internal quality standards and regulatory expectationsDrive continuous improvement in clinical operations processes, tools, and best practicesRequired QualificationsBachelor's degree in a scientific or healthcare-related field (advanced degree preferred)Minimum 10+ years of clinical research experience, including global clinical trials and vendor management5+ years of leadership experience managing clinical trial teams (preferred)Strong knowledge of GCP, ICH guidelines, and global regulatory requirementsProven experience managing complex timelines, budgets, and cross-functional initiativesDemonstrated experience supporting internal and regulatory auditsExcellent communication, negotiation, and stakeholder management skillsAbility to operate effectively in a fast-paced, matrixed environment managing multiple studies and direct reportsPreferred ExperienceRenal Denervation (RDN) clinical trialsCardiology clinical trialsClinical trial people management and team leadership